Akkattu T. Biju

Akkattu T. Biju

Organic Chemistry Division

About Me

We are a team of highly motivated young chemists working on development of transition-metal-free carbon-carbon and carbon-heteroatom bond-forming reactions and their application in organic synthesis.

Professional Experience

  • June 2011- present: Senior Scientist, Organic Chemistry Division, CSIR-NCL, Pune
  • 2008-2011: Alexander von Humboldt Post-doctoral fellow, University of Muenster, mentor : Prof. (Dr.) Frank Glorius
  • 2007-2008: Post-doctoral fellow, National Taiwan University, Taiwan, mentor : Prof. Tien-Yau Luh
  • 2002-2007: Ph. D., Organic Chemistry Division, CSIR-NIIST, Trivandrum, Kerala, mentor : Dr. G. Vijay Nair

Selected Publications

  • Kaicharla T.; Roy T.; Thangaraj M.; Gonnade R. G.; Biju A. T, Lewis Acid Catalyzed Selective Reactions of Donor–Acceptor Cyclopropanes with 2-Naphthols, Angew. Chem. Int. Ed., 55, 10061 - 10064 (2016), DOI:10.1002/anie.201604373.
  • Bhunia A.; Roy T.; Pachfule P.; Rajamohanan P. R.; Biju A. T, Transition-Metal-Free Multicomponent Reactions Involving Arynes, N-Heterocycles and Isatins, Angew. Chem., Int. Ed., 52, 10040 - 10043 (2013), DOI:10.1002/anie.201304278.
    Among the most accessed papers in August 2013, Invited for Synpacts
  • Bhunia A.; Patra A.; Puranik V.; Biju A. T, NHC-Catalyzed Reaction of Enals with Hydroxy Chalcones:Diastereoselective Synthesis of Functionalized Coumarins, Org. Lett., 15, 1756 - 1759 (2013), DOI:10.1021/ol400562z.
    Highlighted in Synfacts 2013, 9, 670.
  • Yetra S. R.; Bhunia A.; Patra A.; Mane M. V.; Vanka K.; Biju A. T, Enantioselective N-Heterocyclic Carbene-Catalyzed Annulations of 2-Bromoenals with 1,3-Dicarbonyl Compounds and Enamines via Chiral alpha,beta-Unsaturated Acyl Azoliums, Adv. Synth. Catal., 355, 1089 - 1097 (2013), DOI:10.1002/adsc.201300219.
  • Kaicharla T.; Yetra S. R.; Roy T.; Biju A. T, Engaging isatins in solvent-free, sterically congested Passerini reaction, Green Chem., 15, 1608 - 1614 (2013), DOI:10.1039/C3GC40454D.
  • Bhunia A.; Porwal D.; Gonnade R. G.; Biju A. T, Multicomponent Reactions Involving Arynes, Quinolines, and Aldehydes, Org. Lett., 15, 4620 - 4623 (2013), DOI:10.1021/ol4023134.
  • Bhojgude S. S.; Kaicharla T.; Biju A. T, Employing Arynes in Transition-Metal-Free Monoarylation of Aromatic Tertiary Amines, Org. Lett., 15, 5452 - 5455 (2013), DOI:10.1021/ol4029258.
    For abstracts in Organic Chemistry Portal, see: http://www.organic-chemistry.org/abstracts/lit4/224.shtm
  • Yetra S. R.; Kaicharla T.; Kunte S. S.; Gonnade R. G.; Biju A. T, Asymmetric N-Heterocyclic Carbene (NHC)-Catalyzed Annulation of Modified Enals with Enolizable Aldehydes, Org. Lett., 15, 5202 - 5205 (2013), DOI:10.1021/ol4026155.
    For abstracts in Organic Chemistry Portal, see: http://www.organic-chemistry.org/abstracts/lit4/202.shtm
  • Nair V.; Menon R. S.; Biju A. T.; Abhilash K. G, 1,2-Benzoquinones in Diels-Alder reactions, dipolar cycloadditions, nucleophilic additions, multicomponent reactions and more, Chem. Soc. Rev., 41, 1050 - 1059 (2012), DOI:10.1039/c1cs15186j.
  • Bhojgude S. S.; Kaicharla T.; Bhunia A.; Biju A. T, A Practical and General Diels-Alder Reaction of Pentafulvenes with Arynes, Org. Lett., 14, 4098 - 4101 (2012), DOI:10.1021/ol301742k.
  • Bhunia A.; Yetra S. R.; Bhojgude S. S.; Biju A. T, Efficient Synthesis of Gamma-Keto Sulfones by NHC-Catalyzed Intermolecular Stetter Reaction, Org. Lett., 14, 2830 - 2833 (2012), DOI:10.1021/ol301045x.
  • Kaicharla T.; Bhojgude S. S. ; Biju A. T, Efficient Diels-Alder Reaction of 1,2-Benzoquinones with Arynes and Its Utility in One-Pot Reactions, Org. Lett., 14, 6238 - 6241 (2012), DOI:10.1021/ol302997q.

Research Interest

  • Organic Chemistry

Contact Details

Dr. Akkattu T. Biju


Senior Scientist
Organic Chemistry Division
CSIR-National Chemical Laboratory
Dr. Homi Bhabha Road
Pune - 411008, India
Phone: +91 20 2590 2441
Fax    : +91 20 2590 2629
E-mail at.biju@ncl.res.in