Benudhar Punji

Benudhar Punji

Organic Chemistry Division

About Me

Our research group is interested in the development of pincer ligand-based organometallic catalysts for small organic molecule activation as well as for various organic transformation through C-H bond activation. Our work involves activation and catalytic functionalizations (alkylations, fluorinations, carboxylations, etc.) of relatively inert C-H bond using inexpensive organometallic complexes of Cobalt, Nickel and Copper salt. Our focus is on the mechanistic-based approach for the development of new catalysts.

Professional Experience

  • 2020 - Current: Senior Principal Scientist, National Chemical Laboratory, Pune, India
  • 2015-2020: Principal Scientist, National Chemical Laboratory, Pune, India
  • 2011-2015: Senior Scientist, National Chemical Laboratory, Pune, India
  • 2010 - 2011 Alexander von Humboldt Post Doctoral Research Fellow (with Prof. Lutz Ackermann, University of Goettingen, Goettingen, Germany
  • 2007 - 2010 NSF-CENTC Post Doctoral Research Fellow (with Prof. Alan S. Goldman, Rutgers-The State University of New Jersey, New Jersey, USA)
  • 2007 Ph.D. (with Prof. M. S. Balakrishna, Indian Institute of Technology, Bombay, Mumbai, India)

Selected Publications

  • S. B. Ankade, A. B. Shabade, V. Soni And B. Punji, Unactivated Alkyl Halides in Transition-Metal-Catalyzed C-H Bond Alkylation, ACS Catal., 11, 3268 - 3292 (2021), DOI:10.1021/acscatal.0c05580.
  • S. B. Ankade, P. P. Samal, V. Soni, R. G. Gonnade, S. Krishnamurty And B. Punji, Ni(II)-Catalyzed Intramolecular C–H/C–H Oxidative Coupling: An Efficient Route to Functionalized Cycloindolones and Indenoindolones, ACS Catal., 11, 12384 - 12393 (2021), DOI:10.1021/acscatal.1c03314.
    Highlighted in "Synfacts, 2021, 17, 1357" by Prof. Mark Lautens
  • R. A. Jagtap, S. K. Verma And B. Punji, MnBr2-Catalyzed Direct and Site-Selective Alkylation of Indoles and Benzo[h]quinoline, Org. Lett., 22, 4643 - 4647 (2020), DOI:10.1021/acs.orglett.0c01398.
  • R. A. Jagtap, P. P. Samal, C. P. Vinod, S. Krishnamurty And B. Punji, Iron-Catalyzed C(sp2)-H Alkylation of Indolines and Benzo[h]quinoline with Unactivated Alkyl Chlorides through Chelation-Assistance, ACS Catal., 10, 7312 - 7321 (2020), DOI:10.1021/acscatal.0c02030.
  • S. M. Khake, V. Soni, R. G. Gonnade And B. Punji, A General Nickel-Catalyzed Method for C-H Bond Alkynylation of Heteroarenes through Chelation Assistance, Chem. Eur. J., 23, 2907 - 2914 (2017).
  • V. Soni, R. A. Jagtap, R. G. Gonnade And B. Punji, Unified Strategy for Nickel-Catalyzed C-2 Alkylation of Indoles through Chelation Assistance, ACS Catal., 6, 5666 - 5672 (2016).
  • S. M. Khake, R. A. Jagtap, Y. B. Dangat, R. G. Gonnade, K. Vanka And B. Punji, Mechanistic Insights into Pincer-Ligated Palladium-Catalyzed Arylation of Azoles with Aryl Iodides: Evidence of a Pd(II)-Pd(IV)-Pd(II) Pathway, Organometallics., 35, 875 - 886 (2016).
  • U. N. Patel, D. K. Pandey, R. G. Gonnade And B. Punji, Synthesis of Quinoline-based NNN-Pincer Nickel(II) Complexes: A Robust and Improved Catalyst System for C–H Bond Alkylation of Azoles with Alkyl Halides, Organometallics., 35, 1785 - 1793 (2016).
  • D. K. Pandey, S. M. Khake, R. G. Gonnade And B. Punji, Mono- and Binuclear Palladacycles via Regioselective C–H Bond Activation: Syntheses, Mechanistic Insights and Catalytic Activity in Direct Arylation of Azoles, RSC Adv., 5, 81502 - 81514 (2015).
  • R. Ahuja, B. Punji, M. Findlater, C. Suplee, W. Schinski, M. Brookhart And A. S. Goldman, Catalytic Dehydroaromatization of n-Alkanes by Pincer-Ligated Iridium Complexes, Nature Chem., 3, 167 - 171 (2011).

Research Interest

  • Catalysis AND NEW methods
  • Synthetic Methodologies
  • Organometallic Chemistry
  • Catalysis & New Methods

Contact Details

Dr. Benudhar Punji

Senior Principal Scientist
RN 230, Main Building, Organic Chemistry Division
CSIR-National Chemical Laboratory
Dr. Homi Bhabha Road
Pune 411008, India
Phone +91 20 2590 2733
Fax +91 20 2590 2621