Kiran A. Kulkarni

Kiran A. Kulkarni

Biochemical Science Division

About Me

Professional Experience

·      March 2013 - Present: Senior Scientist, Division of Biological Sciences National Chemical Laboratory, Pune, India


·      2009 – 2013: Post-doctoral Fellow, Institute of Cancer Research, London.


·      2007 - 2008: Application Scientist, Chemistry And Physics Of Materials Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bengaluru.


·      2000 – 2007: Research Student   Molecular Biophysics from Indian Institute of Science, Bangaluru.

Selected Publications

  • 1. Ioannis Manolaridis*, Kiran Kulkarni*, Roger B. Dodd, Satoshi Ogasawara, Ziguo Zhang, Ganka Bienva, Nicola O’ Reilly, Sarah J. Hanrahan, Andrew J. Thompson, Nora Cronin And So Iwata and David Barford. (* Equal first author), Mechanism of prenylated CAAX protein processing by the integral membrane protease Rce1, Nature., In Press, (2013).
  • William C.H. Chao*, Kiran Kulkarni*, Ziguo Zhang, Eric H. Kong And David Barford (* Equal first author), Structure of the mitotic checkpoint complex, Nature., 484, 208 - 213 (2012).
  • 5. Jing Yang, Kiran Kulkarni, Ioannis Manolaridis, Ziguo Zhang, Roger B. Dodd, Corine Mas-Droux And David Barford , Crystal structure of ICMT reveals the mechanism of CAAX motif postprenyl modification by an integral membrane carboxyl methyltransferase, Mol. Cell., 44, 997 - 1004 (2011).
  • 6. Kulkarni K, Yang J, Zhang Z And Barford D. , Multiple factors confer specific Cdc42 and Rac protein activation by dedicator of cytokinesis (DOCK) nucleotide exchange factors, J. Biol. Chem., 286, 25341 - 25351 (2011).
  • Kulkarni KA, Katiyar S, Surolia A, Vijayan M And Suguna K, Crystal structure of basic winged bean lectin complexed with alpha Gal containing disaccharide with different linkages, Acta Crystallogr D Biol Crystallogr., 64, 730 - 737 (2008).

Research Interest

  • Structure Biology

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