M. Muthukrishnan

M. Muthukrishnan

Organic Chemistry Division

About Me

We work in the field of organic synthesis with our main focus on asymmetric synthesis of biologically significant compounds employing various strategies

We are also interested in developing a strategies in the design and synthesis of novel natural-product like small molecules for various biological applications

Professional Experience

  • 2001- Current- Scientist, National Chemical Laboratory, Pune, India
  • 2003-2004 Post Doctoral Fellow (Kyushu Institute of Technology, Kitakyushu, Japan)
  • 2003 Ph.D Organic Chemistry (TBGRI, Trivandrum) 

Selected Publications

  • N.Viswanadh, ac Ganesh S. Ghotekar, ac Mahesh B. Thoke, a R.Velayudham, a Aslam C. Shaikh And ac M. Karthikeyanbc and M. Muthukrishnan*ac, Transition Metal Free Regio-selective C-H Hydroxylation of Chromanones towards the Synthesis of Hydroxyl-Chromanones using PhI(OAc)2 as Oxidant, Chemical Communications., , (2018), DOI:10.1039/C7CC08588E.
  • Mohammad Mujahid, Jambu Subramanian, Viswanadh Nalla, Murugesan Sasikumar And Sunita Sharad Kuntea and Murugan Muthukrishnan*, A new and efficient enantioselective synthesis of both enantiomers of the calcium channel blocker bepridil, New J. Chem., 41, 824 - 829 (2017), DOI:DOI: 10.1039/c6nj02928k.
  • Mohammad Mujahid*, Prashant Mujumdar, Murugesan Sasikumar, Shirish P. Deshmukh And Murugan Muthukrishnan*, An efficient synthesis of the opioid analgesic (R)-phenampromide via an aziridinium ion, Tetrahedron: Asymmetry., , (2017), DOI:http://dx.doi.org/10.1016/j.tetasy.2017.06.001.
  • M. Mujahid, S. S. Kunte And M. Muthukrishnan*, A new enantioselective synthesis of (S)-2-ethoxy-3-(4-hydroxyphenyl)propanoic acid esters (EEHP and IEHP), useful pharmaceutical intermediates of PPAR agonists, Tetrahedron Letters., 55, 3223 - 3226 (2014), DOI:http://dx.doi.org/10.1016/j.tetlet.2014.04.021.
  • A.Reddi, M. Mujahid, M.Sasikumar And M. Muthukrishnan*, A New Enantioselective Synthesis of the Anti-Parkinson Agent Safinamide, Synthesis., 46, 1751 (2014).
  • M. Mujahid, R. G. Gonnade, P. Yogeeswari, D. Sriram And M. Muthukrishnan, Synthesis and antitubercular activity of amino alcohol fused spirochromone conjugates, Bioorg. Med. Chem. Lett., 23, 1416 (2013).
  • M. Mujahid, P. Mujumdar, M. Sasikumar And M. Muthukrishnan, An alternate synthesis of enantiomerically pure Levetiracetam (Keppra), Tetrahedron: Asymmetry., 23, 1512 - 1515 (2012).
  • M. Muthukrishnan, M. Mujahid, M. Sasikumar And P. Mujumdar, First asymmetric synthesis of the antiepileptic drug Lacosamide (Vimpat) based on a hydrolytic kinetic resolution strategy, Tetrahedron: Asymmetry., 22, 1353 (2011).

Research Interest

Contact Details

Dr. M. Muthukrishnan

Office: 206, Organic Chemistry Division
National Chemical Laboratory
Dr. Homi Bhabha Road
Pune 411008, India
Phone +91 20 2590 2284
Fax +91 20 2590 2629
E-mail m.muthukrishnan@ncl.res.in