Vrushali H. Jadhav

Organic Chemistry Division

About Me

Our group deals with the following areas of research

1. Application of carbohydrates in developing alternative fuels.
2. Synthesis of value added chemicals from biomass.
3. Synthesis of bioactive natural products.

4. Development of valuable synthetic methodologies

Professional Experience

  • Visiting Faculty at University of Leiden, Netherlands in Nov 2015
  • Jan 2013-Current- INSPIRE Faculty, National Chemical Laboratory, Pune, India
  • 2009-2011 Post Doctoral Research Fellow (with Prof.Mikael Bols, University of Copenhagen, Denmark)
  • 2005-2009 Ph.D Research (with Prof. Dilip Dhavale, University of Pune, Pune)

Selected Publications

  • Pramod Rathod And Sagar Nale and Vrushali Jadhav*, Metal Free Acid Base Catalyst in the Selective Synthesis of 2,5-Diformylfuran from Hydroxymethylfurfural, Fructose, and Glucose, ACS Sustainable Chem. Eng., 5, 701 - 707 (2017).
  • Pramod Rathod and Vrushali Jadhav*, Palladium incorporated on carbonaceous catalyst for Suzuki coupling reaction in water, Tetrahedron letters., , (2017).
  • Raju S. Thombal and Vrushali H. Jadhav*, Highly Efficient Sulfonated Graphene Oxide Catalyst for Solvent Less Glycosylation, Journal of Carbohydrate Chemistry., , (2016).
  • Raju S. Thombal and Vrushali H. Jadhav*, Facile O-Glycosylation of Glycals Using Glu-Fe3O4-SO3H, a Magnetic Solid Acid Catalyst, RSC Advances., , (2016), DOI:DOI: 10.1039/C6RA03305A.
  • Sagar D. Nale and Vrushali H. Jadhav*, Synthesis of Tyrosyl-DNA Phosphodiesterase I Inhibitors, Tetrahedron Letters., , (2016), DOI:doi:10.1016/j.tetlet.2016.05.017.
  • Raju S. Thombal and Vrushali H. Jadhav*, Application of Glucose Derived Magnetic Solid Acid for Etherification of 5-HMF to 5-EMF, Dehydration of Sorbitol to Isosorbide and Esterification of Fatty Acids, Tetrahedron Letters., , (2016).
  • Sagar D. Nale and Vrushali H. Jadhav*, Synthesis of Fuel Intermediates from HMF/Fructose, Catalysis letters., , (2016).
  • Raju S. Thombal And Amol R. Jadhav and Vrushali H. Jadhav*, Biomass derived b-cyclodextrin-SO3H as a solid acid catalyst for esterification of carboxylic acids with alcohols, RSC Advances., 5, 12981 - 12986 (2015).
  • Raju S. Thombal and Vrushali H. Jadhav*, Biomass derived -cyclodextrin-SO3H carbonaceous solid acidcatalyst for catalytic conversion of carbohydrates to5-hydroxymethylfurfural, Applied Catalysis A: General., 499, 213 - 216 (2015).
  • Amol Jadhav, Raju Thombal And Preeti Nigam and Vrushali Jadhav*, Synthesis of (±) debenzoyl analogs of norsampsones as potential anticancer agents, Tetrahedron letters., 56, 5235-5237 (2015).
  • Raju S. Thombal and Vrushali H. Jadhav*, Total Synthesis of the Natural Product EBC-329, Org. Biochem. Chem., , (2015), DOI:DOI: 10.1039/C5OB01276G.
  • Raju S. Thombal and Vrushali H. Jadhav*, Efficient One Pot Synthesis of 1,4-Dihydropyridines Under Solvent Free Conditions Using Carbonaceous Solid Acid Catalyst, Journal of Applied Chemistry and Biochemistry., , (2015).
  • Vrushali Jadhav*, Cellulose Hydrolysis: An Unsolved Problem, Research and Reviews Journal of Chemistry., Editorial Article, (2015).
  • Raju S. Thombal and Vrushali H. Jadhav*, Efficient Conversion of Carbohydrates to 5-Hydroxymethylfurfural (HMF) Using ZrCl4 Catalyst in Nitromethane, Biofuel Research Journal., 3, 81 - 84 (2014).
  • Vrushali H. Jadhav And Christian M. Pedersen and Mikael Bols*, A Study of Anhydrocelluloses- Is a Cellulose structure with residues in 1C4 conformation more prone to hydrolysis?, Org. Biochem. Chem., 9, 7525 - 7534 (2011).
  • Vrushali H. Jadhav, Omprakash P. Bande, Vedavati G. Puranik And Dilip D. Dhavale*, Diverse Regioselectivity in the epoxide ring opening in D-Glucose Derived Epoxy Alcohol:Synthesis of Piperidine and Azepane iminosugars, Tetrahedron Asymmetry., 21, 163 - 170 (2010).
  • Vrushali H. Jadhav, Omprakash P. Bande, Vedavati G. Puranik And Dilip D. Dhavale*, Synthesis of eight-membered iminocyclitols from D-glucose, Tetrahedron., 66, 2830 - 2834 (2010).
  • Omprakash P. Bande, Vrushali H. Jadhav And Vedavati G. Puranik and Dilip D. Dhavale*, Synthesis of azepane and nojirimycin iminosugars: the Sharpless asymmetric epoxidation of D-glucose-derived allyl alcohol and highly regioselective epoxide ring opening using sodium azide, Tetrahedron: Asymmetry., 21, 163 - 170 (2010).
  • Vrushali H. Jadhav, Omprakash P. Bande, Rahul V. Pinjari, Shridhar P. Gejji, Vedavati G. Puranik And Dilip D. Dhavale*, Synthesis and Conformational Study of Chiral Oxepines: The Baylis-Hillman Reaction and RCM Approach with Sugar Aldehyde, Journal of Organic Chemistry., 74, 6486 - 6494 (2009).
  • Omprakash P. Bande, Vrushali H. Jadhav, Vedavati G. Puranik And Dilip D. Dhavale* , High Diastereoselective 1,3-Dipolar Cycloaddition of D-Galactose Derived Nitrone with Dimethyl Maleate: Synthesis of Polyhydroxylated Perhydro-azaazulenes, Synlett., 12, 1959 - 1963 (2009).
  • Omprakash P. Bande, Vrushali H. Jadhav And Vedavati G. Puranik and Dilip D. Dhavale*, 1,3-Dipolar cycloaddition reaction of a D-galactose derived nitrone with allyl alcohol: synthesis of polyhydroxylated perhydroazaazulene alkaloids, Tetrahedron: Asymmetry., 18, 1176 - 1182 (2007).
  • Vrushali H. Jadhav, K. S. Ajish Kumar, Vinod D. Chaudhari And and Dilip D. Dhavale, Facile Method for Trimethylsilylation of Alcohols using Hexamethyldisilazane and Ammonium Thiocyanate under Neutral Conditions, Synthetic Communications., 37, 1363 - 1370 (2007).

Research Interest

  • Green & Sustainable Chemistry
  • Basic and Applied aspect of Synthetic Organic Chemistry
  • Synthetic Methodologies
  • Total Synthesis of Biologically Important Natural Products

Contact Details

Dr. Vrushali H. Jadhav


INSPIRE Faculty
Organic Chemistry Division
National Chemical Laboratory
Dr. Homi Bhabha Road
Pune 411008, India
Phone +91 20 2590 2275
E-mail vh.jadhav@ncl.res.in