Total synthesis and methodology development Lab

 CSIR- National Chemical Laboratory, Pune

 Welcome to SBM group

                                                                                                                                                                                                                                                                                                                                                                                                                                                        Dr. Santosh B. Mhaske

Principal Scientist and Associate Professor(AcSIR)
Division of Organic Chemistry
CSIR-National Chemical Laboratory (NCL)
Dr. Homi Bhabha Road
Pune 411008, India
Phone: +91 20 2590 2440
Lab: +91 20 2590 2573
Fax: +91 20 2590 2629
E-mail: sb.mhaske@ncl.res.in  

Recent Publications:

 "Phosphine-Free Manganese(II)-Catalyst Enables Acceptorless Dehydrogenative Coupling of Alcohols with Indole"

 Vinita Yadav, Ekambaram Balaraman, Santosh B. Mhaske

 Adv. Synth. Catal., (2021)

"Annulation of Enals with Carbamoylpropiolates via NHC-Catalyzed Enolate Pathway: Access to Functionalized Maleimides/Iso-maleimides and Synthesis of Aspergillus FH-X-213"

Amol B. Viveki,^§ Mahesh D. Pol,^§ Priyanka Halder, Sameer R. Sonavane, and Santosh B. Mhaske* (§Equal Contribution)

J. Org. Chem., 86, 14, 9466–9477 (2021)            

"Photoactivable Prodrug for Simultaneous Release of Mertansine, and CO along with a BODIPY Derivative as a Luminescent Marker in Mitochondria: A Proof of Concept for NIR Image-Guided Cancer Therapy"

Rajeshwari Tiwari^‡, Prashant S. Shinde^‡,Sreejesh Sreedharan^‡, Anik Kumar Dey, Katherine A. Vallis*, Santosh B. Mhaske*, Sumit Kumar Pramanik* and Amitava Das* (‡Equal Contribution)

Chem. Sci., 12, 2667-2673 (2021)

"Construction of Unique SCF3-Containing Building Blocks via Allylic Alkylation of Morita-Baylis-Hillman Adducts"   

 Priyanka Halder, Mahesh D. Pol, Milind M. Ahire and Santosh B. Mhaske*

Org. Biomol. Chem., 18, 2085 - 2093 (2020) 

"para-Selective copper-catalyzed C(sp2)–H amidation/dimerization of anilides via a radical pathway" 

 Amol B. Viveki, Dnyaneshwar N. Garad, Rajesh G. Gonnade and Santosh B. Mhaske* 

 Chem. Commun., 56, 1565 - 1568 (2020)

  "Stereoselective construction of deoxy-cruciferane alkaloids by NHC-catalyzed intramolecular annulation of homoenolate with quinazolinone" 

 Milind M. Ahire, Mahesh D. Pol, Dattatry S. Kavale, Rajesh G. Gonnade and Santosh B. Mhaske*

  Org. Biomol. Chem., 17, 7135 - 7139 (2019)

“Ru-Catalyzed Regioselective Cascade Annulation of Acrylamides with 2-Alkynoates for the Synthesis of Various 6-Oxo Nicotinic Acid Esters”

 Dnyaneshwar N. Garad and Santosh B. Mhaske*

 J. Org. Chem., 84, 1863 - 1870 (2019)