Total Synthesis, Medicinal chemistry and Methodology Development

CSIR-National Chemical Laboratory, Pune

The team of highly motivated young chemists in Dr. Chavan’s group at CSIR-NCL, Pune is involved in the total synthesis of bioactive natural products and medicinally important drug molecules along with development of new synthetic methodologies.

December 2019: Appasaheb's research paper on "Furan Derived Chiral Bicycloaziridino Lactone Synthon: Collective Syntheses of Oseltamivir Phosphate (Tamiflu), (S)-Pipecolic acid and its 3-Hydroxy Derivatives" has been accepted in Chemistry-An Asian Journal.

Congratulations!!!

November 2019: Sanket's research paper on "Formal Synthesis of Brivaracetam: A Key to Construct the Pyrrolidone Scaffold Using Pd-Catalyzed Oxidative Cyclization and Ring-Closing Metathesis Reaction" has been accepted in Tetrahedron Letters.

Congratulations!!!
October 2019: Appasaheb's research paper on"Enantioselective Formal Total Synthesis of (‒)-Quinagolide" has been accepted in Organic Letters.

Congratulations!!!

May 2019: Appasaheb's research paper on "Total Synthesis of (±)-Quinagolide: A Potent D2 Receptor Agonist for the Treatment of Hyperprolactinemia" has been accepted in ACS Omega.

Congratulations!!!
November 2018: Appasaheb's research paper on "Synthesis of 3‑Azidopiperidine Skeleton Employing Ceric Ammonium Nitrate (CAN)-Mediated Regioselective Azidoalkoxylation of Enol Ether: Total Synthesis of D₂ Receptor Agonist (±)-Quinagolide" has been accepted in Organic Letters.

Congratulations!!!