Anu Raghunathan



Systems biology, Metabolic engineering, Antibiotic resistance, Brain Cancer metabolism,

Synthetic Biology,Constraints-based Flux Balance Analysis.

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2013- Current: Principal Scientist, National Chemical Laboratory, Pune, India

2009- 2013: Senior Scientist, National Chemical Laboratory, Pune, India

2006-2009: Faculty, Infectious Diseases Division,

Mount Sinai School of Medicine, New York, NY

2002-2005: Post Doctoral Research Associate (with Prof. Bernhard Palsson), 

University of California, San Diego, La Jolla, CA

2000-2002: Post Doctoral Research Associate (with Prof. Lonnie Ingram and James preston)



MP Rajankar , S Ravindranathan, PR Rajamohanan and A Raghunathan. 

Absolute Quantitation Of Poly(R)-3-Hydroxybutyric Acid Using Spectrofluorometry 
In Recombinant Escherichia Coli. Oxford Academic-Biology Methods and Protocols. (Accepted, 2018)
SRC Immanuel*, D Banerjee*, MP Rajankar*, A Raghunathan. Integrated Constraints Based
Analysis Of An Engineered Violacein Pathway In Escherichia coli. Biosystems 171, 10 - 19, 2018.
DOI: 10.1016/j.biosystems.2018.06.002
(* Equal contributors)
D Banerjee, A Raghunathan. Knowledge, attitude and practice of antibiotic use and antimicrobial
resistance: a study post the'Red Line'initiative. Current Science (00113891) 114 (9), 2018. 
DOI: 10.18520/cs/v114/i09/1866-1877
SRC Immanuel, AD Ghanate, DS Parmar, F Marriage, V Panchagnula, Philip J Day, A Raghunathan.
Integrative analysis of rewired central metabolism in temozolomide resistant cells.
Biochemical and biophysical research communications 495 (2), 2010-2016, 2018. 
DOI: 10.1016/j.bbrc.2017.12.073
A Raghunathan, N Jamshidi. Integrated Host-Pathogen Metabolic Reconstructions.
Metabolic Network Reconstruction and Modeling, 197-217, 2018.
D Banerjee, D Parmar, N Bhattacharya, AD Ghanate, V Panchagnula, A Raghunathan.
A scalable metabolite supplementation strategy against antibiotic resistant pathogen 
Chromobacterium violaceum induced by NAD+/NADH+ imbalance. 
BMC systems biology 11 (1), 51 3, 2017. Full Text
A Raghunathan, CA Athale. Modelling natural and synthetic biological networks.
Current Science 113 (7), 1221-1222, 2017.
N Jamshidi, A Raghunathan. Cell scale host-pathogen modeling: another branch
in the evolution of constraint-based methods. Frontiers in microbiology 6, 1032 5, 2015. 
DOI: 10.3389/fmicb.2015.01032
PP Sadhukhan, A Raghunathan. Investigating host–pathogen behavior and their interaction
using genome-scale metabolic network models. Immunoinformatics, 523-562, 6, 2014. 
DOI: 10.1007/978-1-4939-1115-8_29
I Thiele, DR Hyduke, B Steeb, G Fankam, DK Allen, S Bazzani, ... BO Palsson. A community
effort towards a knowledge-base and mathematical model of the human pathogen 
Salmonella Typhimurium LT2. BMC systems biology 5 (1), 8 105 2011. DOI: 10.1186/1752-0509-5-8
A Raghunathan, J Reed, S Shin, B Palsson, S Daefler. Constraint-based analysis of metabolic
capacity of Salmonella typhimurium during host-pathogen interaction. 
BMC systems biology 3 (1), 38, 149, 2009. DOI: 10.1186/1752-0509-3-38
CD Herring, A Raghunathan, C Honisch, T Patel, MK Applebee, AR Joyce, TJ Albert, FR Blattner, 
DVD Boom, CR Cantor, BØ Palsson. Comparative genome sequencing of Escherichia coli allows
observation of bacterial evolution on a laboratory timescale. 
Nature genetics 38 (12), 1406 330, 2006. DOI: 10.1038/ng1906
C Honisch, A Raghunathan, CR Cantor, BØ Palsson, D van den Boom. 
High-throughput mutation detection underlying adaptive evolution of Escherichia coli-K12.
Genome research 14 (12), 2495-2502 49, 2004. DOI: 10.1101/gr.2977704
A Raghunathan, ND Price, MY Galperin, KS Makarova, S Purvine, ... In silico metabolic model
and protein expression of Haemophilus influenzae strain Rd KW20 in rich medium. 
Omics: a journal of integrative biology 8 (1), 25-41, 2004. 

DOI: 10.1089/153623104773547471