Neurodegenerative diseases – misfolding and aggregation

Modified nucleic acid analogs

Molecular dynamics simulations

Research Experience:

2013 – 2018          Postdoctoral Fellow          The University of Texas at Austin

                                                                      Advisor: Prof. Dmitrii E. Makarov


2010 – 2013          Postdoctoral Fellow          The University of British Columbia

                                                                         Advisor: Dr. Steven S. Plotkin


2005 – 2010                   Ph. D.                                University of Calcutta

                                                                    Advisor: Prof. Chaitali Mukhopadhyay



2003 – 2005                 M. Sc.                                University of Calcutta

2000 – 2003                 B. Sc.                                 University of Calcutta



Dr. Santosh Jha, CSIR-NCL, India 

Dr. Durba Sengupta, CSIR-NCL, India 

Prof. Eric V. Anslyn, Department of Chemistry, University of Texas Austin, USA

Dr. Neeladri Das, Department of Chemistry, Indian Institute of Technology Patna, India 


Selected List of Publications:


A. Das*, J. Phys. Chem. B 125, 12177-12186 (2021) Systematic search for a predictor for the clinical observables of Alzheimer's disease.

A. Das, D. E. Makarov*, J. Phys. Chem. B 122, 9049-9060 (2018) Dynamics of disordered proteins under confinement: memory effects and internal friction.

A. Das, S. S. Plotkin*, Proc. Natl. Acad. Sci. USA 110, 3871-3876 (2013) SOD1 exhibits allosteric frustration to facilitate metal binding affinity.

A. Das, C. Mukhopadhyay*, J. Phys. Chem. B 113, 12816-12824 (2009) Urea-mediated protein denaturation: A consensus view.