Research Interest:
- Asymmetric synthesis of biologically interesting compounds
- Development of new synthetic methodologies
- Photochemistry by using Electron Donar-Acceptor (EDA) complex
- Bioorganic chemistry
Professional Experience
- 2001- Current- Scientist, National Chemical Laboratory, Pune, India
- 2003-2004 Post Doctoral Fellow (Kyushu Institute of Technology, Kitakyushu, Japan)
- 2003 Ph.D Organic Chemistry (TBGRI, Trivandrum)
Selected Publications
- M. Mujahid, P. Mujumdar, M. Sasikumar, M. Muthukrishnan, An alternate synthesis of enantiomerically pure Levetiracetam (Keppra®), Tetrahedron: Asymmetry, 2012 (in press).
- M. Muthukrishnan, M. Mujahid, M. Sasikumar, P. Mujumdar, “First asymmetric synthesis of the antiepileptic drug Lacosamide (Vimpat®) based on a hydrolytic kinetic resolution strategy, Tetrahedron: Asymmetry, 2011, 22, 1353.
- M. Muthukrishnan, M. Mujahid, P. Yogeeswari, D. Sriram, Synthesis and biological evaluation triazole fused spirochromone conjugates as inhibitors of Mycobacterium Tuberculosis, Tetrahedron Lett., 2011, 52, 2387.
- M. D. Nikalje, M. Sasikumar, M. Muthukrishnan, A facile enantioselective synthesis of enantiomerically pure (R)-phenoxybenzamine hydrochloride using hydrolytic kinetic resolution method, Tetrahedron: Asymmetry, 2010, 21, 2825.
- M. Sasikumar, M. D. Nikalje, M. Muthukrishnan, A convenient synthesis of enantiomerically pure (R)-mexiletine using hydrolytic kinetic resolution method, Tetrahedron: Asymmetry, 2009, 20, 2814.
- M. Muthukrishnan, U. M. V. Basavanag, V. G. Puranik, The first ionic liquid-promoted kabbe condensation reaction for an expeditious synthesis of privileged bis-spirochromanone scaffolds, Tetrahedron Lett., 2009, 50, 2643.
- M. Muthukrishnan, D. R. Garud , R. R. Joshi, R. A. Joshi, “Concise synthesis of β-blockers (S)-Metoprolol and (S)-Betaxolol using hydrolytic kinetic resolution, Tetrahedron ,2007, 63, 1872.
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