Research Group Publications

 
  • Sachin R. Shirsath, Ganesh S. Ghotekar, Vir Bahadur, Rajesh G. Gonnade And and M. Muthukrishnan*, Silver-Catalyzed Cascade Cyclization/1,6-Conjugate Addition of Homopropargyl Sulfonamides to p-Quinone Methides: An Approach to Diverse 3-Diarylmethine Substituted Dihydropyrroles, The Journal of Organic Chemistry., 85, 15038 - 15050 (2020), DOI:https://doi.org/10.1021/acs.joc.0c01922.
  • Ganesh S. Ghotekar, Sachin R. Shirsath And Aslam C. Shaikh and M. Muthukrishnan*, 1,6-Conjugate addition initiated formal [4+2] annulation of p-quinone methides with sulfonyl allenols: a unique access to spiro[5.5]undeca-1,4-dien-3-one scaffolds, Chemical Communications., 56, 5022 - 5025 (2020), DOI:https://doi.org/10.1039/D0CC01005G.
  • Ganesh S. Ghotekar, Devidas A. More, Viswanadh Nalla And M. Muthukrishnan*, A new enantioselective synthesis of antiobesity drug lorcaserin, New Journal of Chemistry., 43, 16876 - 16880 (2019), DOI:10.1039/C9NJ04234B.
  • Devidas A. More, Ganesh H. Shinde, Aslam C. Shaikh And M. Muthukrishnan*, Oxone promoted dehydrogenative Povarov cyclization of N-aryl glycine derivatives: an approach towards quinoline fused lactones and lactams†, RSC Advances., 9, 30277 - 30291 (2019), DOI:10.1039/C9RA06212B.
  • Ganesh S. Ghotekar, M. Mujahid And M. Muthukrishnan*, Efficient Synthesis of Optically Active Neolignans Ligraminol D and E, Synthesis., 51, 4291 - 4295 (2019), DOI:10.1055/s-0037-1611919.
  • Ganesh S. Ghotekar, Aslam C. Shaikh And M. Muthukrishnan*, Transition-Metal-Free Benzannulation of Tricarbonyl Derivatives with Arynes: Access to 1,3-Dinaphthol Precursors for the Synthesis of Rhodamine Dye Analogues, The Journal of Organic Chemistry., 84, 2269 - 2276 (2019), DOI:10.1021/acs.joc.8b02560.
  • Ganesh S. Ghotekar, Mohammad Mujahid And M. Muthukrishnan*, Total Synthesis of Marine Natural Products Serinolamide A and Columbamide D, ACS Omega., 4, 1322 - 1328 (2019), DOI:10.1021/acsomega.8b03417.
  • Sachin R. Shirsath, Ganesh H. Shinde, Aslam C. Shaikh And M. Muthukrishnan* , Accessing alpha Arylated Nitriles via BF3·OEt2 Catalyzed Cyanation of para-Quinone Methides Using tert-Butyl Isocyanide as a Cyanide Source, The Journal of Organic Chemistry., 83, 12305 - 12314 (2018), DOI:10.1021/acs.joc.8b01926.
  • Viswanadh Nalla , Aslam Shaikh , Sanket Bapat , Renu Vyas , M. Karthikeyan , P. Yogeeswari , D. Sriram And M. Muthukrishnan*, Identification of potent chromone embedded [1,2,3]-triazoles as novel anti-tubercular agents, Royal Society Open Science., 5, 171750 (2018), DOI:https://doi.org/10.1098/rsos.171750.
  • N.Viswanadh, Ganesh S. Ghotekar, Mahesh B. Thoke, R.Velayudham, Aslam C. Shaikh, M. Karthikeyanbc And M. Muthukrishnan*, Transition Metal Free Regio-selective C-H Hydroxylation of Chromanones towards the Synthesis of Hydroxyl-Chromanones using PhI(OAc)2 as Oxidant, Chemical Communications., , (2018), DOI:10.1039/C7CC08588E.
  • Mohammad Mujahid*, Prashant Mujumdar, Murugesan Sasikumar, Shirish P. Deshmukh And Murugan Muthukrishnan*, An efficient synthesis of the opioid analgesic (R)-phenampromide via an aziridinium ion, Tetrahedron: Asymmetry., 28, 983 - 986 (2017), DOI:http://dx.doi.org/10.1016/j.tetasy.2017.06.001.
  • Mohammad Mujahid, Jambu Subramanian, Viswanadh Nalla, Murugesan Sasikumar And Sunita Sharad Kuntea and Murugan Muthukrishnan*, A new and efficient enantioselective synthesis of both enantiomers of the calcium channel blocker bepridil, New J. Chem., 41, 824 - 829 (2017), DOI:10.1039/c6nj02928k.
  • N. Viswanadh, P. Mujumdar, M. Sasikumar, S. S. Kunte And M. Muthukrishnan* , An alternate synthesis of appetite suppressant (R)-2-benzylmorpholine employing Sharpless asymmetric epoxidation strategy, Tetrahedon Letters., 57, 861 (2016).
  • R. Vyas, M. Karthikeyan, G. Nainaru And M. Muthukrishanan, Pharmacophore and docking based virtual screening of validated Mycobacterium, J Comb Chem H Tr Scrn., 18, 624 (2015).
  • M. Mujahid, P. Yogeeswari, D. Sriram, U. M. V. Basavanag, E. D. Cervantes, L. C. Bahena, J. Robles, R. G. Gonnade, M. Karthikeyan, R. Vyas And M. Muthukrishnan* , Spirochromone-chalcone conjugates as antitubercular agents: synthesis, bio evaluation and molecular modeling studies, RSC Adv., 5, 106448 (2015).
  • N. Viswanadh, R. Velayudham, S. Jambu, S. Sasikumar And M. Muthukrishnan* , Chiral aziridine ring opening: Facile synthesis of (R)-mexiletine and (R)-phenoxy benzamine hydrochloride, Tetrahedon Letters., 56, 5269 (2015).
  • M. Mujahid, S. S. Kunte And M. Muthukrishnan*, A new enantioselective synthesis of (S)-2-ethoxy-3-(4-hydroxyphenyl)propanoic acid esters (EEHP and IEHP), useful pharmaceutical intermediates of PPAR agonists, Tetrahedon Letters., 55, 3223 (2014).
  • A.Reddi, M. Mujahid, M.Sasikumar And M. Muthukrishnan*, A New Enantioselective Synthesis of the Anti-Parkinson Agent Safinamide, Synthesis., 46, 1751 - 1756 (2014), DOI:10.1055/s-0033-1341104.
  • M. Mujahid, S. S. Kunte And M. Muthukrishnan*, A new enantioselective synthesis of (S)-2-ethoxy-3-(4-hydroxyphenyl)propanoic acid esters (EEHP and IEHP), useful pharmaceutical intermediates of PPAR agonists, Tetrahedron Letters., 55, 3223 - 3226 (2014), DOI:http://dx.doi.org/10.1016/j.tetlet.2014.04.021.
  • M. Mujahid, R. G. Gonnade, P. Yogeeswari, D. Sriram And M. Muthukrishnan, Synthesis and antitubercular activity of amino alcohol fused spirochromone conjugates, Bioorg. Med. Chem. Lett., 23, 1416 (2013).
  • M. Mujahid And M. Muthukrishnan, A new enantioselective synthesis of the anticonvulsant drug pregabalin (Lyrica) based on a hydrolytic kinetic resolution method, Chirality., 25, 965 (2013).
  • M. Mujahid, P. Mujumdar, M. Sasikumar And M. Muthukrishnan, An alternate synthesis of enantiomerically pure Levetiracetam (Keppra), Tetrahedron: Asymmetry., 23, 1512 - 1515 (2012).
  • M. Muthukrishnan, M. Mujahid, P. Yogeeswari And D. Sriram, Synthesis and biological evaluation triazole fused spirochromone conjugates as inhibitors of Mycobacterium Tuberculosis, Tetrahedron Lett., 52, 2387 (2011).
  • M. Muthukrishnan, M. Mujahid, M. Sasikumar And P. Mujumdar, First asymmetric synthesis of the antiepileptic drug Lacosamide (Vimpat) based on a hydrolytic kinetic resolution strategy, Tetrahedron: Asymmetry., 22, 1353 (2011).
  • M. D. Nikalje, M. Sasikumar And M. Muthukrishnan, A facile enantioselective synthesis of enantiomerically pure (R)-phenoxybenzamine hydrochloride using hydrolytic kinetic resolution method, Tetrahedron: Asymmetry., 21, 2825 (2010).
  • M. Muthukrishnan, M. Mujahid, V. Punitharasu And D.A. Dnyaneshwar, A simple and efficient synthesis of 2-aryl-2,3-dihydroquinolin-4(1H)-ones using silica chloride as a new catalyst under solvent free conditions, Synth. Commun., 40, 1391 (2010).
  • M. Sasikumar, M. D. Nikalje And M. Muthukrishnan, A convenient synthesis of enantiomerically pure (R)-mexiletine using hydrolytic kinetic resolution method, Tetrahedron: Asymmetry., 20, 2814 (2009).
  • M. Muthukrishnan, U. M. V. Basavanag And V. G. Puranik, The first ionic liquid-promoted kabbe condensation reaction for an expeditious synthesis of privileged bis-spirochromanone scaffolds, Tetrahedron Lett., 50, 2643 (2009).
  • M. Muthukrishnan And Om V. Singh, Thallium(III) p-tosylate mediated oxidative 2,3-aryl rearrangement: A new useful route to ipriflavone and its analogs, Synth. Commun., 38, 3875 (2008).
  • M. Muthukrishnan, D. R. Garud , R. R. Joshi And R. A. Joshi, Concise synthesis of , Tetrahedron., 63, 1872 (2007).
  • ? M. Muthukrishnan, S. V. More, D. R. Garud, C. V. Ramana, R. R. Joshi And R. A. Joshi, Pictet-Spengler cyclization in room temperature ionic liquid: A convenient access to tetrahydro- , J. Heterocyclic. Chem., 43, 767 (2006).
  • O. V. Singh, M. Muthukrishnan And S. Sundaravadivelu, Thallium(III) nitrate mediated ring contraction 0f 2-Aryl-1,2,3,4-tetrahydro-4-quinolones: stereoselective synthesis of trans Methyl 2-aryl-2,3-dihydroindol-3-carboxylates, Synth. Commun., 36, 943 (2006).
  • R. A. Joshi, D. R. Garud, M. Muthukrishnan, R. R. Joshi And M. K. Gurjar, A convenient synthesis of optically pure , Tetrahedron: Asymmetry., 16, 3802 (2005).
  • O. V. Singh, M. Muthukrishnan And S. Sundaravadivelu, Synthesis of isoflavones containing naturally occurring substitution pattern by oxidative rearrangement of respective flavanones using thallium(III) p-tosylate, Indian J. Chem., 44B, 2575 (2005).
  • O. V. Singh, M. Muthukrishnan And Gopan Raj, Manganese(III) acetate mediated oxidation of flavanones: A facile synthesis of flavones, Synth. Commun., 35, 2723 (2005).
  • M. Muthukrishnan, P. S. Patil, S. V. More And R. A. Joshi, Facile oxidation of flavanone to flavone using [hydroxy(tosyloxy)iodo]benzene in room temperature ionic liquid, Mendeleev Commun., , 100 (2005).
  • R. A. Joshi, P. S. Patil, M. Muthukrishnan, C. V. Ramana And M. K. Gurjar, Copper-mediated coupling of aminopurines and aminopyrimidines with arylboronic acids, Tetrahedron Lett., 45, 195 (2004).
  • V. George, M. Muthukrishnan And T. Chojnacki, The occurrence of polyprenols in Euphorbiaceae, Acta. Bot. Polon., 70, 39 (2001).
  • O. V. Singh, M. Muthukrishnan And S. Sundaravadivelu, Thallium(III) salts in heterocyclic synthesis: synthesis of 3-aryl-9-methyl-1,2,4-triazolo[4,3-a] quinolines, Indian J. Chem., 40B, 262 (2001).