Research Group Publications
 
  • Sharad Sarak, Amol D Pagar, Taresh P Khobragade, Hyunwoo Jeon, Pritam Giri, Seonga Lim, Mahesh D Patil, Ye Chan Kim, Byung-Gee Kim And Hyungdon Yun, Multienzyme Biocatalytic Cascade as a Route Towards Synthesis of a,w-diamines from Corresponding Cycloalkanols, Green Chemistry., 25, 543 - 549 (2023), DOI:10.1039/D2GC03392E (IF-11.03).
  • Hee-Wang Yoo, Hyunsang Jung, Sharad Sarak, Ye Chan Kim, Beom Gi Park, Byung-Gee Kim, Mahesh D. Patil And Hyungdon Yun, Multi-Enzymatic Cascade Reactions With Escherichia Coli-Based Modules For Synthesizing Various Bioplastic Monomers From Fatty Acid Methyl Esters, Green Chemistry., 24, 2222 - 2231 (2022), DOI:10.1039/D1GC04532F (IF- 11.034).
  • Hyunwoo Jeon, Amol D Pagar, Hyeona Kang, Pritam Giri, Saravanan P Nadarajan, Sharad Sarak, Taresh P Khobragade, Seonga Lim, Mahesh D Patil, Sun-Gu Lee And Hyungdon Yun, Creation of a (R)-w-Transaminase by Directed Evolution of d-Amino Acid Aminotransferase, ACS Catalysis., 12, 13207 - 13214 (2022), DOI:10.1021/acscatal.2c04221 (IF-13.700).
  • Mahesh D. Patil, # Amol D. Pagar, # Dillon T. Flood, Tae Hyeon Yoo, Philip E. Dawson And Hyungdon Yun, Recent Advances in Biocatalysis with Chemical Modification and Expanded Amino Acids Alphabet, Chemical Reviews., 121, 6173 - 6245 (2021), DOI:10.1021/acs.chemrev.0c01201 (IF-72.087) # Equal contribution.
  • Gopal Patel, Mahesh D Patil, Sujit Tangadpalliwar, Shivraj Hariram Nile, Prabha Garg, Guoyin Kai And Uttam Chand Banerjee, Machine Learning Modeling for Ultrasonication-Mediated Fermentation of Penicillium brevicompactum to Enhance the Release of Mycophenolic Acid, Ultrasound in Medicine & Biology., 47, 777 - 786 (2021), DOI:10.1016/j.ultrasmedbio.2020.11.018 (IF-3.694).
  • Taresh P Khobragade, Seongseon Yu, Hyunsang Jung, Mahesh D Patil, Sharad Sarak, … And Hyungdon Yun, Promoter Engineering?mediated Tuning of Esterase and Transaminase Expression for the Chemoenzymatic Synthesis of Sitagliptin Phosphate at the kilogram?scale, Biotechnology and Bioengineering., 118, 3263 - 3268 (2021), DOI:10.1002/bit.27819 (IF-4.395).
  • Pritam Giri# Amol D. Pagar# Mahesh D. Patil And Hyungdon Yun, Chemical Modification of Enzymes to Improve Biocatalytic Performance, Biotechnology Advances., 53, 107868 (2021), DOI:10.1016/j.biotechadv.2021.107868 (IF-17.681) # Equal contribution.
  • Gopal Patel, Neeraj Singh Thakur, Varun Kushwah, Mahesh D Patil, Shivraj Hariram Nile, Sanyog Jain, Guoyin Kai And Uttam Chand Banerjee, Mycophenolate co-administration with quercetin via lipid-polymer hybrid nanoparticles for enhanced breast cancer management, Nanomedicine: Nanotechnology, Biology and Medicine., 24, 102147 (2020), DOI:10.1016/j.nano.2019.102147 (IF-6.458).
  • Gopal Patel, Neeraj Singh Thakur, Varun Kushwah, Mahesh D Patil, Shivraj Hariram Nile, Sanyog Jain, Uttam Chand Banerjee And Guoyin Kai, Liposomal delivery of mycophenolic acid with quercetin for improved breast cancer therapy in SD rats, Frontiers in Bioengineering and Biotechnology., 8, 631 (2020), DOI:10.3389/fbioe.2020.00631 (IF- 6.064).
  • Gopal Patel, Taresh P Khobragade, Sachin R Avaghade, Mahesh D Patil, Shivraj Hariram Nile, Guoyin Kai And Uttam Chand Banerjee, Optimization of media and culture conditions for the production of tacrolimus by Streptomyces tsukubaensis in shake flask and fermenter level, Biocatalysis and Agricultural Biotechnology., 29, 101803 (2020), DOI:10.1016/j.bcab.2020.101803 (IF- 4).
  • Sharad Sarak, Hyunwoo Jeon, Mahesh D Patil, Taresh P Khobragade, Amol D Pagar, Sihyong Sung, Hee Wang Yoo, Byung Gee Kim, Sung Ho Yoon And Hyungdon Yun, Enzymatic Synthesis of Aliphatic Primary ??Amino Alcohols from ??Amino Fatty Acids by Carboxylic Acid Reductase, Catalysis Letters., 150, 3079 - 3085 (2020), DOI:10.1007/s10562-020-03233-9 (IF-2.936).
  • Sharad Sarak, Sihyong Sung, Hyunwoo Jeon, Mahesh D Patil, Taresh P Khobragade, Amol D Pagar, Philip E Dawson And Hyungdon Yun, An Integrated Cofactor/Co?Product Recycling Cascade for the Biosynthesis of Nylon Monomers from Cycloalkylamines, Angewandte Chemie International Edition., 60, 3481 - 3486 (2020), DOI:10.1002/anie.202012658 (IF-16.823).
  • Geon-Hee Kim, Hyunwoo Jeon, Taresh P. Khobragade, Mahesh D Patil, Sihyong Sung, Sanghan Yoon, Yumi Won, In Suk Choi And Hyungdon Yun, Enzymatic synthesis of sitagliptin intermediate using a novel w-transaminase, Enzyme and Microbial Technology., 120, 52 - 60 (2019), DOI:10.1016/j.enzmictec.2018.10.003 (IF-3.705).
  • Mahesh D Patil, # Sanghan Yoon, # Sharad Sarak, Hyunwoo Jeon, Geon-Hee Kim, Taresh P Khobragade, Sihyong Sung And Hyungdon Yun, Deracemization of Racemic Amines to Enantiopure (R)- and (S)-amines by Biocatalytic Cascade Employing w-Transaminase and Amine Dehydrogenase, ChemCatChem., 11, 1898 - 1902 (2019), DOI:10.1002/cctc.201900080 (IF-5.501); #Equal authorship.
  • Geon-Hee Kim, Hyunwoo Jeon, Taresh P Khobragade, Mahesh D Patil, Sihyong Sung, Sanghan Yoon, Yumi Won, Sharad Sarak And Hyungdon Yun, Glutamate as an Efficient Amine Donor for the Synthesis of Chiral B-and gamma-Amino Acids Using Transaminase, ChemCatChem., 11, 1437 - 1440 (2019), DOI:10.1002/cctc.201802048 (IF-5.501).
  • Yumi Won, Amol D Pagar, Mahesh D Patil, Philip E Dawson And Hyungdon Yun, Recent Advances in Enzyme Engineering through Incorporation of Unnatural Amino Acids, Biotechnology and Bioprocess Engineering., 24, 592 - 604 (2019), DOI:10.1007/s12257-019-0163-x (IF-3.386).
  • Mahesh D. Patil, Vijay P. Rathod, Umesh R. Bihade And Uttam Chand Banerjee, Purification and characterization of arginine deiminase from Pseudomonas putida: Structural insights of the differential affinities of L-arginine analogues, Journal of Bioscience and Bioengineering., 127, 129 - 137 (2019), DOI:10.1016/j.jbiosc.2018.07.021 (IF-3.185).
  • Kiran D Bhilare, Mahesh D Patil, Sujit Tangadpalliwar, Ashok Shinde, Prabha Garg And Uttam Chand Banerjee, Machine Learning Modelling for the Ultrasonication-Mediated Disruption of Recombinant E. Coli for the Efficient Release of Nitrilase, Ultrasonics., 98, 72 - 81 (2019), DOI:10.1016/j.ultras.2019.06.006 (IF-4.062).
  • Mahesh D Patil, Sanghan Yoon, Hyunwoo Jeon, Taresh P Khobragade, Sharad Sarak, Amol D Pagar, Yumi Won And Hyungdon Yun, Kinetic Resolution of Racemic Amines to Enantiopure (S)-amines by a Biocatalytic Cascade Employing Amine Dehydrogenase and Alanine Dehydrogenase, Catalysts., 9, 600 (2019), DOI:10.3390/catal9070600 (IF-4.501).
  • Hee-Wang Yoo, Joonwon Kim, Mahesh D Patil, Beom Gi Park, Sung-yeon Joo, Hyungdon Yun And Byung-Gee Kim, Production of 12-Hydroxy Dodecanoic Acid Methyl Ester using a Signal Peptide Sequence-Optimized Transporter Alkl and a Novel Monooxygenase, Bioresource Technology., 291, 121812 (2019), DOI:10.1016/j.biortech.2019.121812 (IF-11.889).
  • Yumi Won, Hyunwoo Jeon, Amol D. Pagar, Mahesh D. Patil, Saravanan P. Nadarajan, Dillon T. Flood, Philip E. Dawson And Hyungdon Yun, In Vivo Biosynthesis of Tyrosine Analogs and Their Direct Incorporation in a Residue-Specific Manner For Enzyme Engineering, Chemical Communications., 55, 15133 - 15136 (2019), DOI:10.1039/C9CC08503C (IF-6.065).
  • Sihyong Sung, Hyunwoo Jeon, Sharad Sarak, Md Murshidul Ahsan, Mahesh D. Patil, Wolfgang Kroutil, Byung-Gee Kim And Hyungdon Yun, Parallel anti-sense two-step cascade for alcohol amination leading to w-amino fatty acids and a,w-diamines, Green Chemistry., 20, 4591 - 4595 (2018), DOI:10.1039/C8GC02122H (IF-11.034).
  • Mahesh D. Patil, Gideon Grogan, Andreas S. Bommarius And Hyungdon Yun, Oxidoreductase-Catalyzed Synthesis of Chiral Amines, ACS Catalysis., 8, 10985 - 11015 (2018), DOI:10.1021/acscatal.8b02924 (IF-13.700).
  • Mahesh D. Patil, Gideon Grogan And Andreas Bommarius and Hyungdon Yun, Recent Advances in w-Transaminase-Mediated Biocatalysis for the Enantioselective Synthesis of Chiral Amines, Catalysts., 8, 254 (2018), DOI:10.3390/catal8070254 (IF-4.501).
  • Md Ahsan, Mahesh D. Patil, Hyunwoo Jeon, Sihyong Sung, Taeowan Chung And Hyungdon Yun, Biosynthesis of Nylon 12 Monomer, w-Aminododecanoic Acid Using Artificial Self-Sufficient P450, AlkJ and w-TA, Catalysts., 8, 400 (2018), DOI:10.3390/catal8090400 (IF-4.501).
  • Md Murshidul Ahsan, Sihyong Sung, Hyunwoo Jeon, Mahesh D. Patil, Taeowan Chung And Hyungdon Yun, Biosynthesis of Medium-to Long-Chain a,w-Diols from Free Fatty Acids Using CYP153A Monooxygenase, Carboxylic Acid Reductase, and E. coli Endogenous Aldehyde Reductases, Catalysts., 8, 4 (2018), DOI:10.3390/catal8010004 (IF-4.501).
  • Hyunwoo Jeon, Sharad Sarak, Sang-Hyuk Lee, Han-Seop Bea, Mahesh D. Patil, Geon-Hee Kim, Byung-Gee Kim, Jong In Won And Hyungdon Yun, Characterization of ELP-fused w-Transaminase and Its Application for the Biosynthesis of B-Amino Acid, Biotechnology and Bioprocess Engineering., 23, 481 - 489 (2018), DOI:10.1007/s12257-018-0268-7 (IF-3.386).
  • Mahesh D. Patil, Gideon Grogan And Hyungdon Yun, Biocatalyzed C-C Bond Formation for the Production of Alkaloids, ChemCatChem., 10, 4783 - 4804 (2018), DOI:10.1002/cctc.201801130 (IF-5.501).
  • Mahesh D. Patil, Ashok S. Shinde, Gopal Patel, Kiran D. Bhilare And Manoj J. Dev and Uttam Chand Banerjee, Combined Effect of Attrition and Ultrasound on the Disruption of Pseudomonas putida for the Efficient Release of Arginine Deiminase, Biotechnology Progress., 34, 1185 - 1194 (2018), DOI:10.1002/btpr.2664 (IF-2.909).
  • Gopal Patel, Kush Biswas, Mahesh D. Patil, Yusuf Chisti And Uttam Chand Banerjee, Bioreactor studies of production of mycophenolic acid by Penicillium brevicompactum, Biochemical Engineering Journal., 140, 77 - 84 (2018), DOI:Biochemical Engineering Journal.
  • Mahesh D. Patil, Manoj J. Dev, Sujit Tangadpalliwar, Gopal Patel, Prabha Garg, Yusuf Chisti And Uttam Chand Banerjee, Ultrasonic disruption of Pseudomonas putida for the release of arginine deiminase: Kinetics and predictive models, Bioresource Technology., 233, 74 - 83 (2017), DOI:10.1016/j.biortech.2017.02.074 (IF-11.4).
  • Md. Murshidul Ahsan, Hyunwoo Jeon Saravanan P. Nadarajan, Taeowan Chung, Hee-Wang Yoo, Byung-Gee Kim, Mahesh D. Patil And and Hyungdon Yun, Biosynthesis of the nylon 12 monomer, w-Aminododecanoic acid with novel CYP153A, AlkJ, and w-TA enzymes, Biotechnology Journal., 13, 1700562 (2017), DOI:10.1002/biot.201700562 (IF-5.7).
  • Gopal Patel, Mahesh D. Patil, Surbhi Soni, Yusuf Chisti And Uttam Chand Banerjee, Production of mycophenolic acid by Penicillium brevicompactum using solid state fermentation, Applied Biochemistry and Biotechnology., 182, 97 - 109 (2017), DOI:10.1007/s12010-016-2313-3 (IF-3.094).
  • Mahesh D. Patil, Manoj J. Dev, Ashok Shinde, Kiran D. Bhilare, Gopal Patel, Yusuf Chisti And Uttam Chand Banerjee, Surfactant-mediated permeabilization of Pseudomonas putida and its immobilization for the biotransformation of L-arginine to L-citrulline, Process Biochemistry., 63, 113 - 121 (2017), DOI:10.1016/j.procbio.2017.08.002 (IF-4.885).
  • Gopal Patel, Mahesh D. Patil, Surbhi Soni, Taresh P. Khobragade, Yusuf Chisti And Uttam Chand Banerjee, Production of mycophenolic acid by Penicillium brevicompactum- A comparison of two methods of optimization, Biotechnology Reports., 11, 77 - 85 (2016), DOI:10.1016/j.btre.2016.07.003 (CiteScore- 12.8).
  • Mahesh D. Patil, Gopal Patel, Balaji Surywanshi, Naeem Shaikh, Prabha Garg, Yusuf Chisti And Uttam Chand Banerjee, Disruption of Pseudomonas putida by high pressure homogenization: a comparison of the predictive capacity of three process models for the efficient release of arginine deiminase, AMB Express., 6, 84 (2016), DOI:10.1186/s13568-016-0260-6 (IF-4.0).
  • Mahesh D. Patil, Kiran D. Shinde, Gopal Patel, Yusuf Chisti And Utaam Chand Banerjee, Use of response surface method for maximizing the production of arginine deiminase by Pseudomonas putida, Biotechnology Reports., 10, 29 - 37 (2016), DOI:10.1016/j.btre.2016.03.002 (CiteScore- 12.8).
  • Mahesh D. Patil, Jayeeta Bhaumik, Suboj Babykutty, Uttam Chand Banerjee And Dai Fukumura, Arginine dependence of tumor cells: targeting a chink in cancer’s armor, Nature-Oncogene., 35, 4957 - 4972 (2016), DOI:10.1038/onc.2016.37 (IF-8.8).