Ø Respiratory system: Experience
in various preclinical models of asthma (such as early and late asthmatic response,
broncho-constriction, allergic inflammation models)
Ø Musculoskeletal system:
Experience in preclinical models of osteoarthritis
Ø Cytokine Research: Assay
development and validation of assay, measurement of allegen specific IgE in the
lung, Measurement of cytokines in lung lavage fluids and identification of
cells in lung lavage fluids.
Ø Diabetes: In-collaboration
Ø Cancer therapeutics
Employment & Organizational details:
Chemical Laboratory: Biochemical Sciences Division
(23rd , April,2015 onwards)
(2) CSIR-Indian Institute of Toxicology Research, formerly known as Industrial
Toxicology Research Centre, Lucknow, India.
Email:firstname.lastname@example.org Website: www.iitrindia.org
(3) Jai Research
Foundation, Vapi, Gujarat, India.Jai
Research Foundation.JRF is
Laboratory Practice (GLP) accredited contract research organization (CRO).
Email: email@example.com, Website: www.jrfonline.com
1) Life member, Society of Toxicology, India. Membership no- 719L
2) Life member, Society for Toxicologic Pathology
in India. Membership no-1090
3) Life member, Laboratory Animal Scientists
Association. Membership no-8169
4) Life member, Indian Association of
Veterinary Pathologists.Memebership no-IAVP/P-90/2010.
Admitted as Associate of Academy of Sciences
for Animal welfare. (F 153/2008)
Academy of Sciences for Animal Welfare
- Completed training course on Good
Laboratory Practice conducted at Jai Research Foundation, Valvada, India
on 4th December, 2001.
- Completed the
training course on Good Laboratory Practice conducted at Jai Research
Foundation, Valvada, Gujarat by N.J.Dent on behalf of country consultancy
Ltd., U.K. on 16th Feb. 2002 at Vapi, India.
- Participated on Laboratory Quality system &
Internal Audit as per ISO/IEC 17025 organized by National
Accreditation Board for testing & calibration Laboratories during 1-4
Sept.2003 at Jaipur, India.
workshop on Good laboratory practices (GLP) jointly organized by
UNDP/world bank/WHO ,National GLP compliance monitoring authority, DST,CDRI on 3-5
Dec.2003 at New Delhi, India
- Participated at
the “Alternatives, Animal Welfare
and the Curriculum’’ seminar and workshop on 28th
August,2004 at Lucknow ,India organized by International Network for
Education and The World Society for the Protection of Animals in conjunction
with People for animals.
- Participated in
the national GLP conference organized by GLP monitoring authority of India
on January 13-15, 2005 at Indian Institute of Toxicology Research,
- Attended the
training workshop on Non-clinical
Safety testing organized by UNICEF/UNDP/World Bank/Who-TDR & CDRI
on 24-26 October, 2005 at New Delhi, India.
- Participated in
the National consultation on Herbo-metallic
preparations of Indian Systems of medicine; Safety & Quality
standardization held on March 3-4, 2006 at INSA New Delhi
- Participated in
the international workshop on Toxicology towards Diplomate of American
Board of Toxicology conducted by Curtis Klassen at Advinus Therapeutics
Pvt.Ltd.Bangalore from 8-12 October 2007.
- Participated in
the 1st Annual course in Toxicologic Pathology-Road to
Toxico-pathology jointly organized by Charles Luis Davis, D.V.M.
Foundation and Society for Toxicologic Pathology in India at Pune, India
on 13-15, March, 2008.
as a “Trainer” at WHO-TDR, workshop on “Train the GLP
Trainer” jointly organized by UNDP/World bank/WHO special programme for
research and Training in Tropical Diseases (TDR) & IITR, Lucknow on
13-18 October 2008.
completed the distance learning “General
course on Intellectual Property” from October 1 to November
10, 2009 conducted by world Intellectual Property organization.
- Participated in
the workshop and training programme on Sampling and Detection Methods Applied to Transgenic Crops on
November 17-19, 2011 at National Institute of Nutrition, Hyderabad, India.
List of SCI publications:
Rhabdomyosarcoma in wistar
rats.M.C.Prasad, D.P.Kadam,G.Sonawane,B.P.Chaudhari,J.Maheshkumar. Indian
Journal of Environment & Toxicology Vol.N.11,issue-2,84-85,December 2001.
2. Effect of
fly ash inhalation on biochemical and histomprphological changes in rat liver.
U.Mani, A.K.Prasad,V.Sureshkumar,Kewal Lal,B.P.Chaudhari,R.C.Murthy.
Ecotoxicol. Environment. Safety 68:126-133. 2007.
Comparative studies of different organs of Nyctanthes arbortristis in modulation of
cytokines in murine model of arhritis.Brijesh Rathore,Bholanath Paul,Bhushan P.Chaudhari,Ashok Kumar
Saxena,Anand Prakash Sahu and Yogendra Kumar Gupta.Biomedical and Environmental
sciences, 20, 154-159. 2007.
Status of Stat3 in an Ovalbumin induced mouse
model of asthma: analysis of the role of Socs3 an IL1-6. Bholanath Paul, Vani Mishra , Bhushan Chaudhari , Anjali Awasthi ,Asim Bikas Das, Urmila
Saxena, Ashok Saxena, Lalit K. Chauhan,Pradeep Kumar, Sheikh
Raisuddin. International Archives of allergy and immunology Vol.148,
Partial characterization of red
gram (Cajanus cajan L. Millsp) polypeptides recognized by patients exhibiting
rhinitis and bronchial asthma.Amita Misra, Rahul Kumar ,Vivek
P. Chaudhari, Anurag Tripathi, Mukul Das,Premendra D. Dwivedi. Food and
Chemical Toxicology 48 (2010) 2725–2736.
6. IL-6 receptor-mediated lung Th2 cytokine networking in silica-induced
pulmonary fibrosis.Shambhoo Sharan Tripathi, Vani
Mishra,Mamta Shukla,Mukesh Verma,Bhushan Pradosh Chaudhari,Pradeep
Kumar,Jasmeet Kaur Chhabra,Haushila Prasad Pandey, Bholanath Paul. Arch Toxicol (2010) 84:947-955.
Probiotic Enterococcus lactis IITRHR1 protects
against acetaminophen induced hepatotoxicity.Sapna Sharma, Jaya Chaturvedi,
Bhusan P Chaudhari, R.L Singh, Poonam Kakkar. Nutrition, 28
Carryover of cigarette smoke effects on
hematopoietic cytokines to F1 mouse litters Mamta Shukla,Pradeep Kumar, Vani
Mishra,Bhushan Pradosh Chaudhari ,
Ashok Kumar Munjal,Shambhoo Sharan Tripathi, Seikh Raisuddin, Bhola Nath Paul.
Accepted 9 May 2011, Molecular Immunology. vol. 48, no. 15-16, pp. 1809–1817, 2011.
Allergenic responses of red kidney bean
(Phaseolus vulgaris cv chitra) polypeptides in BALB/c mice recognized by
bronchial asthma and allergic rhinitis patients.
Sandeep Kumar , Alok Kumar Verma , Amita Misra , Anurag Tripathi , Bhushan P. Chaudhari ,Rajendra Prasad ,
S.K. Jain, Mukul Das , Premendra D. Dwivedi.Food Research International.44
Potential allergens of green gram (Vigna
radiata L. Millsp) identified as members of cupin superfamily and seed albumin.
A. Misra, R. Kumar,V. Mishra,B.P.
Chaudhari,S. Raisuddin,M. Das and P. D. Dwivedi. Clinical &
Experimental Allergy, 41,157–1168, issue 8,(2011)
Role of mitogen activated protein kinases in
skin tumorigenicity of Patulin. Neha Saxena, Kausar M. Ansari, Rahul Kumar, Bhushan P. Chaudhari,Premendra D.
Dwivedi, Mukul Das. Toxicology and Applied Pharmacology,volume 257, issue,
Studies in Murine Model of Asthma:Effect of Stat3 siRNA. Bhushan
Chaudhari, Pankaj Jagdale, Sheikh Raisuddin, Shambhoo Sharan Tripathi,
Mamta Shukla, Pradeep Kumar Singh, Pradeep Kumar Journal of
Applied Pharmaceutical Science 01 (10); 2011: 77-84
- Edible oil adulterants, argemone oil and butter yellow, as
aetiological factors for gall bladder cancer. Vivek Mishra, Manjari Mishra , Kausar
M. Ansari , Bhushan P. Chaudhari,Raj Khanna , Mukul Das.
European Journal of Cancer. 11/2011;48(13):2075-85doi:10.1016/j.ejca.2011.09.026.
(Cicer arietinum) proteins induce allergic responses in nasobronchial
allergic patients and BALB/c mice. Alok Kumar Vermaa, Sandeep Kumar,
Anurag Tripathi, Bhushan P.
Chaudhari, Mukul Das, Premendra D. Dwivedi. Toxicology Letters 210
(2012) 24– 33
- Natural Terpenes
Prevent Mitochondrial Dysfunction, Oxidative Stress and Release of
Apoptotic Proteins During Nimesulide-Induced Hepatotoxicity in Rats.
Brijesh Kumar Singh,MadhulikaTripathi,Bhushan
P. Chaudhari,Pramod K Pandey, Poonam Kakkar.PLos ONE Volune 7,issue
A-induced cell proliferation and tumor promotion in mouse skin by
activating the expression of cyclin-D1 and cyclooxygenase-2 through
nuclear factor-kappa B and activator protein-1.Rahul
Kumar, Shamshad Alam, Bhushan P.Chaudhari, Premendra D.Dwivedi,
Swatantra K.Jain,Kausar M.Ansari and Mukul Das.Carcinogenesis vol.00
no.00 p.1 of 11, 2012, doi:10.1093/carcin/bgs368
- Topical Application of Ochratoxin A
Causes DNA Damage and Tumor Initiation in Mouse Skin.Rahul Kumar, Kausar
M. Ansari, Bhushan P. Chaudhari,
Alok Dhawan, Premendra D. Dwivedi,Swatantra K. Jain, Mukul Das.PLOS
ONE,October 2012 | Volume 7, Issue 10, e47280
- Anomalies in ovary following oral
exposure to oxytocin: Mechanistic studies.
Manjari Mishra, Vivek Mishra, Bhushan
P. Chaudhari, Vinay K. Khanna, Sanjay Mehrotra,Shakir Ali , Mukul Das. Reproductive Toxicology 40 (2013) 24– 34
- Ellagic acid attenuates bleomycin and
cyclophosphamide-induced pulmonary toxicity in Wistar rats. Saba , Somaira
Khan , Suhel Parvez , Bhushan
Chaudhari , Firoz Ahmad , Sameya Anjum ,Sheikh Raisuddin. Food and
Chemical Toxicology 58 (2013) 210–219
- Allergenicity potential of red kidney
bean (Phaseolus vulgaris L.) proteins in orally treated BALB/c mice and
passively sensitized RBL-2H3 cells. Sandeep
Kumar, Akanksha Sharma, Alok K. Verma, B.P. Chaudhari, Mukul Das , S.K. Jain ,Premendra D. Dwivedi.Cellular
Immunology. 284 (2013) 37–44
- In-Vivo Efficacy of
Compliant 3D Nano-Composite in Critical-Size Bone Defect Repair: a Six
Month Preclinical Study in Rabbit. Nitin Sagar, Alok K. Pandey,
Deepak Gurbani, Kainat Khan, Dhirendra Singh, Bhushan P. Chaudhari,Vivek
P. Soni, Naibedya Chattopadhyay, Alok Dhawan, Jayesh R. Bellare.PLOS ONEOctober 2013, Volume 8, Issue 10, e77578
- Zinc oxide
nanoparticles provide an adjuvant effect to ovalbumin via a Th2 response
in Balb/c mice. Ruchi Roy, Sandeep Kumar, Alok K. Verma, Akanksha
Sharma, Bhushan P. Chaudhari,Anurag Tripathi, Mukul Das and Premendra D. Dwivedi.
International Immunology. doi:10.1093/intimm/dxt053
augment red kidney bean (Phaseolus vulgaris L.) induced allergic
manifestations.Sandeep Kumar, Alok Kumar Verma, Akanksha Sharma, Dinesh
Kumar,Anurag Tripathi, B.P.
Chaudhari, Mukul Das, S.K. Jain, Premendra D. Dwivedi.Journol of
proteomics (2013). Nov 20;93:50-64
- Hypersensitivity linked to exposure
of Broad bean protein(s) in allergic patients and BALB/c mice.Dinesh Kumar, Sandeep Kumar, Alok K. Verma, , Akanksha Sharma, Anurag Tripathi, Bhushan P. Chaudhari, Surya Kant, , Mukul Das, Swatantra K. Jain, Premendra D. Dwivedi, Nutrition (2013)
- Phaseolin: A 47.5 kDa protein
of red kidney bean (Phaseolus vulgaris L.) plays a pivotal role in
hypersensitivity induction. Int. Immunopharmacol. 2014;19(1),
178–190. Kumar S, Verma AK, Sharma A, Roy R, Kumar D, Giridhar BH,
Tripathi A, Chaudhari BP, Das M, Jain SK, Dwivedi PD
inhibits in vitro adipogenesis arresting mitotic clonal expansion and improves dyslipidemia in vivo.Salil
Varshney, Kripa Shankar, Muheeb Beg, Vishal M. Balaramnavar, Sunil Kumar
Mishra,Pankaj Jagdale , Shishir Srivastava , Yashpal S. Chhonker , Vijai
Lakshmi ,Bhushan P. Chaudhari ,
Rabi Shankar Bhatta , Anil Kumar Saxena
and Anil Nilkanth Gaikwad.Journal of Lipid Research, doi: 10.1194/jlr.M039925
- Association between children death and
consumption of Cassia occidentalis seeds: Clinical and experimental
investigations. Gatikrushna Panigrahi, Shashikant Tiwari, Kausar M. Ansari,
Rajnish K. Chaturvedi,Vinay K. Khanna, Bhushan P. Chaudhari, Vipin M. Vashistha,S. Raisuddin, Mukul
Das. Food and Chemical Toxicology 67 (2014) 236–248
- Deoxynivalenol induced mouse
skin cell proliferation and inflammation via MAPKs pathway”Sakshi Mishra,Anurag
D.Dwivedi,Haushila P.Pandey,Mukul Das.TToxicology and Applied
Pharmacology.doi:10.1016/j.taap.2014.06.003( In Press, Available online 15
- Evaluation of three-dimentional
chitosan-agarose-gelatin cryogel scaffold for the repair of subchondral
cartilage defects: an in vivo study in a rabbit model.Ankur Gupta,Sumrita
Bhat,Pankaj R. Jagdale,Bhushan
P.Chaudhari,Las Lidgren,Kailash C.Gupta,Ashok Kumar, Tissue Eng Part A,doi:10.1089/ten.TEA.2013.0702,2014
ZnO nanoparticles induced adjuvant effect via
toll-like receptors and 2 Src signaling in Balb/c mice.Ruchi Roy , Dinesh Kumar
, Akanksha Sharma , Parul Gupta, Bhushan
P. Chaudhari , Anurag Tripathi , Mukul Das , Premendra D. Dwivedi
(Accepted) Toxicology Letters
Allergic manifestation by black gram (Vigna
mungo) proteins in allergic patients, BALB/c mice and RBL-2H3 cells. Alok Kumar
Verma , Sandeep Kumar , Akanksha Sharma , Dinesh Kumar , Ruchi Roy,Rinkesh
Kumar Gupta, Bhushan P. Chaudhari,
B.H. Giridhar, Mukul Das, Premendra D. Dwivedi. International
Immunopharmacology 23 (2014) 92–103
Elucidation of immediate type I reactions in
native and GM mustard (Brassica spp.). Akanksha Sharma, Sandeep Kumar, Rinkesh
Kumar Gupta, Ruchi Roy, Kriti Gupta,Alok Kumar Verma, Bhushan P. Chaudhari,
Mukul Das, Premendra D. Dwivedi. Food Research International 64 (2014) 810–821
Oil and Butter Yellow Induced Toxicity in Hepatic and Extra Hepatic Tissues Vivek Mishra, Manjari Mishra, Bhushan P
Chaudhari, Raj Khanna and Mukul Das, Bioenergetics (2014) 3: 111.
factory-derived bioactive molecules with polymeric cryogel scaffold enhance the
repair of subchondral cartilage defect in rabbits.Ankur Gupta, Sumrita Bhat, Bhushan P. Chaudhari, Kailash C. Gupta,
Magnus Tägil, Ming Hao Zheng, Ashok Kumar and Lars Lidgren. Journal of tissue
engineering and regenerative medicine (2015) Published online in Wiley Online
Library (wileyonlinelibrary.com) DOI: 10.1002/term.2063
Brain Barrier Delivery of Dopamine-Loaded Nanoparticles Reverses Functional
Deﬁcits in Parkinsonian Rats.Richa Pahuja, Kavita Seth, Anshi Shukla, Rajendra
Kumar Shukla, Priyanka Bhatnagar, Lalit Kumar Singh Chauhan, Prem Narain
Saxena, Jharna Arun, Bhushan Pradosh Chaudhari, Devendra
Kumar Patel, Sheelendra Pratap Singh, Rakesh Shukla, Vinay Kumar Khanna,Pradeep
Kumar, Rajnish Kumar Chaturvedi, and Kailash Chand Gupta..ACS Nano,Vol