Utpal Das

Utpal Das

Organic Chemistry Division

About Me

We are working on the development of new synthetic methodologies and asymmetric catalysis with particular emphasis on ‘Organocatalysis’ for the synthesis of enantioenriched compounds of biological and medicinal importance.

Current available position: Two PhD positions is available in our group






Professional Experience

  1. July 2014 - present: Scientist, Organic Chemistry Division, CSIR-NCL, Pune.
  2. January 2011 - May 2014: Post-doctoral fellow, National Taiwan Normal University, Taiwan, Advisor: Prof. Wenwei Lin.
  3. November 2009 – October 2010: Post-doctoral fellow, Université de Bourgogne, France, Advisor: Prof. Sylvain Jugé.
  4. 2009: Ph. D., School of Chemistry, University of Hyderabad, Prof. D. Basavaiah.

Selected Publications

  • Archana Rai And Utpal Das*, Accessing meta-Enone-Substituted Anisoles using ArN2BF4 as Precatalyst via Rearrangement of Alkyne-Tethered Cyclohexadienones, Synthesis., 56, A - H (2024), DOI:10.1055/a-2331-9439.
  • Someshwar B. Kale, Tejaswini A patil And Utpal Das*, Rongalite as a C1 Source: Sulfonylmethylation of Indoles with Aryl/Alkyl- Hydrazides and Sulfinates, J. Org. Chem. (Accepted)., NA, - - - (2024), DOI:NA.
  • Pawan Kumar, Archana Rai, Manish Kumar, Gamidi Rama Krishna And Utpal Das*, Radical Cascade Cyclization of Unactivated Alkene-Tethered Indoles with Aryldiazonium Salt and Sodium Metabisulfite to Access Azo- and Sulfonylated-2,3-Dihyro-1H-pyrrolo[1,2-a]indoles, J. Org. Chem., 13, 9123 - 9129 (2023), DOI:10.1021/acs.joc.3c00759.
  • Someshwar B. Kale, Manish Kumar, Dinesh R. Shinde, Gamidi Rama Krishna And Utpal Das*, Synthesis of N-functionalized 2,3-disubstituted benzofurans/naphthofurans from para-quinone methides and isocyanides via the [4 + 1] annulation pathway, Org. Chem. Front., 10, 3746 - 3751 (2023), DOI:10.1039/D3QO00048F.
  • Someshwar B. Kale, Popat K. Jori And Utpal Das*, Rongalite as a Sulfone Source: Sulfonylation of para -Quinone Methides and Alkyl/allyl Halides, Chemistry-An Asian Journal., xx, xxxx - xxxx (2022), DOI:10.1002/asia.202200408.
  • Siddharth K. Deepake, Manish Kumar, Pawan Kumar And Utpal Das*, alpha-Angelica Lactone Catalysed Oxidation of Pyrrolidines to Lactams, Eur. J. Org. Chem., , xxxx - xxxx (2022), DOI:10.1002/ejoc.202200712.
  • Pawan Kumar, Someshwar B. Kale, Rajesh G. Gonnade And Utpal Das*, Acid Mediated Sulfonylation of para-Quinone Methides with Tosylmethyl Isocyanides for the Synthesis of Diarylmethyl Sulfones, ChemistrySelect., 6, 7158 - 7161 (2021), DOI:10.1002/slct.202102272.
  • Thanusha Thatikonda, ‡ Siddharth K. Deepake‡ Pawan Kumar And Utpal Das*, alpha-Angelica lactone catalyzed oxidation of benzylic sp3 C–H bonds of isochromans and phthalans, Org. Biomol. Chem., 18, 4046 - 4050 (2020), DOI:10.1039/D0OB00729C. ‡ These authors contributed equally.
  • Someshwar B. Kale, Popat K. Jori, Thanusha Thatikonda, Rajesh G. Gonnade And Utpal Das*, 1,6-Conjugate-Addition-Induced [2 + 1] Annulation of para-Quinone Methides and Pyrazolones: Synthesis of Bis-Spiro Compounds with Contiguous Quaternary Spiro-Centers, Organic Letters., 21, 7736 - 7740 (2019), DOI:10.1021/acs.orglett.9b02641.
  • Thanusha Thatikonda, Siddharth K. Deepake And Utpal Das*, alpha-Angelica Lactone in a New Role: Facile Access to N-Aryl Tetrahydroisoquinolinones and Isoindolinones via Organocatalytic alpha-CH2 Oxygenation, Organic Letters., 21, 2532 - 2535 (2019), DOI:10.1021/acs.orglett.9b00224.
  • S. K. Deepake, A. B. Lanjewar, T. Thatikonda And R. G. Gonnade Utpal. Das*, Organocatalytic Asymmetric Cascade Reaction of gamma-Substituted Deconjugated Butenolides with o-Formyl-beta-nitrostyrene, ChemistrySelect., 3, 8189 - 8192 (2018), DOI:10.1002/slct.201801467.
  • Anil K. Mahida And Someshwar B. Kale and Utpal Das*, Synthesis Route to Pyrrolones from alpha-Beta Cyano -Unsaturated Ketones and alpha-Isocyano Esters by Oxidative Dearomatization of 2-Aminofuran Intermediates, Eur. J. Org. Chem., , 6427 - 6433 (2017), DOI:10.1002/ejoc.201701194.
  • Utpal Das And Yi-Ling Tsai and Wenwei Lin, Chemoselective Intramolecular Wittig Reaction for the Synthesis of Functionalized Heterocycles (a perspective review article), Org. Biomol. Chem., 12, 4044 - 4050 (2014).
  • Utpal Das And Yi-Ling Tsai and Wenwei Lin , An efficient organocatalytic enantioselective synthesis of spironitrocyclopropanes (Selected as an Organic & Biomolecular Chemistry HOT Article), Org. Biomol. Chem., 11, 44 - 47 (2013).
  • Utpal Das, Yi-Ru Chen And Yi-Ling Tsai and Wenwei Lin, Organocatalytic Enantioselective Direct Vinylogous Michael Addition of ?-Substituted Butenolides to 3-Aroyl Acrylates and 1,2-Diaroylethylenes, Chem. Eur. J., 19, 7713 - 7717 (2013).
  • Yen-Te Lee, Utpal Das, Yi-Ru Chen, Chia-Jui Lee, Chi-Han Chen, Mei-Chun Yang And and Wenwei Lin, Enantioselective Synthesis of Coumarin Derivatives Catalyzed by Primary Amine, Adv. Synth. Catal., 355, 3154 - 3160 (2013).
  • Utpal Das And Chan-Hui Huang and Wenwei Lin, Enantioselective synthesis of substituted pyrans via amine-catalyzed Michael addition and subsequent enolization/cyclisation, Chem. Commun., 48, 5590 - 5592 (2012).

Research Interest

  • Organic Chemistry

Contact Details


Dr. Utpal Das

Scientist, Organic Chemistry Division

(Room 211, Main Building)

CSIR-National Chemical Laboratory

Dr. Homi Bhabha Road, Pune - 411008, India

Phone: +91 20 2590 2303

E-mail u.das@ncl.res.in / dutpal10@gmail.com