Research Interest:

  • Modeling of reaction networks
  • Simulation of biological systems using deterministic and stochastic models
  • Mathematical Analysis
  • Disease and drug delivery modeling

Professional Experience

  • 2017-Current Associate Dean (Engineering Science), AcSIR, India
  • 2006- Current Scientist, National Chemical Laboratory, Pune, India
  • 2008-Current Scientist, Institute of Genomics and Integrative Biology, New Delhi, India
  • 2006-2007 Mathematical Modeler (Investigator - grade), GlaxoSmithKline, King of Prussia, Pennsylvania, USA
  • 2004-2006 Mathematical Modeler (Scientist - grade), GlaxoSmithKline, Research Triangle Park, North Carolina, USA
  • 2001-2004 Postdoctoral Associate, School of Mathematics, University of Minnesota, USA

Academic Background

  • 1996-2001 Ph.D. Chemical Engineering and Materials Science Department, University of Minnesota, USA
  • 1994-1996 M Tech, Chemical Engineering Department, IIT Bombay
  • 1990-1995 B Chem Eng, ICT Mumbai

Selected Publications

(For complete list please see

  • Iyengar, B.R., Pillai, B., Venkatesh, K.V. and *Gadgil, C.J. 2017. Systematic comparison of the response properties of protein and RNA mediated gene regulatory motifs. Mol. BioSyst., 2017, DOI: 10.1039/C6MB00808A
  • Puntambekar, S. S, Nyayanit, D., Saxena, P., and *Gadgil, C. J. 2016. Identification of unintuitive features of sumoylation through mathematical modeling. J Biol Chem. 291: 9458-9468.
  • Nyayanit, D., and *Gadgil, C. J. 2015. Mathematical modelling of combinatorial regulation suggests that apparent positive regulation of targets by miRNA could be an artifact resulting from competition for mRNA. RNA. 21(3):307-319
  • Gokhale, S., Hariharan, M., *Brahmachari, S.K., and *Gadgil, C.J. 2012. A simple method for incorporating dynamic effects of intronic miRNA mediated regulation. Mol. BioSyst. 8 (8), 2145 - 2152.
  • Gokhale, S and *Gadgil, C.J. 2012. A mathematical model identifies conditions for ‘unexpected’ increase in target protein levels due to miRNA regulation. Mol. BioSyst., 8 (3), 760-765
  • Subramanian, K., and *Gadgil, C. J. 2010. Robustness of the Drosophila segment polarity network to transient perturbations. IET Systems Biology. 4(2): 169-176
  • Gadgil, C.J., 2009. Size-independent differences between the mean of discrete stochastic systems and the corresponding continuous deterministic systems. Bulletin of Mathematical Biology. 71: 1599-1611
  • Gadgil, C.J., Kulkarni, B.D. 2009. Autocatalysis in Biological Systems. AIChE Journal. 55(3): 556-562
  • !Gadgil, C.J., !Lee, C.-H!., and *!Othmer, H.G. 2005. Stochastic model for first order reaction networks. Bull. Math. Biol. 67:901-946
  • Gadgil, C.J., Yeckel, A., Derby, J., and *Hu, W.-S. 2004. A diffusion-reaction model for cDNA hybridization on a microarray. J Biotechnol. 114(1-2):31-45
  • !Dillon, R., !Gadgil, C.J., and *Othmer, H.G. 2003. Short- and long-range effects of Sonic hedgehog in limb development. PNAS. 100(18): 10152-10157