Biomolecules for Neurodegenerative diseases

Our research mainly focus on the development of novel biomolecules, which could act as inhibitors for Asynuclein.  Human neurodegenerative diseases such as Parkinson’s disease (PD), Alzheimer’s disease (AD) and Prion diseases are the result of protein misfolding and subsequent self-association into insoluble amyloid fibrils. Understanding the molecular mechanisms and the pathophysiology of these brain disorders is a topic of intense research and the development of treatments is the major challenges to date. We are involved in developing inhibitors for Asynuclein fibrillation which can interact  through electrostatic and hydrophobic interactions.

Supramolecular Biopolymers

We are also involved in the development of amphiphilic peptide - polymer systems, which could self assemble to form micellar structures.