Publications:

1: Chattopadhyay G, Bhowmick J, Manjunath K, Ahmed S, Goyal P, Varadarajan R. Mechanistic insights into global suppressors of protein folding defects. PLoSGenet. 2022 Aug 29;18(8). 

 
2: Lolli ML, Carnovale IM, Pippione AC, Wahlgren WY, Bonanni D, Marini E, Zonari D, Gallicchio M, Boscaro V, Goyal P, Friemann R, Rolando B, Bagnati R, Adinolfi S, Oliaro-Bosso S, Boschi D. Bioisosteres of Indomethacin as Inhibitors of Aldo-Keto Reductase 1C3. ACS Med Chem Lett. 2019 Jan 28;10(4):437-443. 
 
3: Pippione AC, Sainas S, Goyal P, Fritzson I, Cassiano GC, Giraudo A, Giorgis M, Tavella TA, Bagnati R, Rolando B, Caing-Carlsson R, Costa FTM, Andrade CH,Al-Karadaghi S, Boschi D, Friemann R, Lolli ML. Hydroxyazole scaffold-basedPlasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis,biological evaluation and X-ray structural studies. Eur J Med Chem. 2019 Feb1;163:266-280. 
 
4: Sainas S, Pippione AC, Lupino E, Giorgis M, Circosta P, Gaidano V, Goyal P,Bonanni D, Rolando B, Cignetti A, Ducime A, Andersson M, Järvå M, Friemann R,Piccinini M, Ramondetti C, Buccinnà B, Al-Karadaghi S, Boschi D, Saglio G, LolliML. Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors. J MedChem. 2018 Jul 26;61(14):6034-6055. Epub 2018Jul 9. Erratum in: J Med Chem. 2019 Feb 14;62(3):1696. PMID: 29939742. 
 
5: Wahlgren WY, Dunevall E, North RA, Paz A, Scalise M, Bisignano P, Bengtsson-Palme J, Goyal P, Claesson E, Caing-Carlsson R, Andersson R, Beis K, Nilsson UJ,Farewell A, Pochini L, Indiveri C, Grabe M, Dobson RCJ, Abramson J, Ramaswamy S,Friemann R. Substrate-bound outward-open structure of a Na<sup>+</sup>-coupledsialic acid symporter reveals a new Na<sup>+</sup> site. Nat Commun. 2018 May1;9(1):1753. 
 
6: Pippione AC, Carnovale IM, Bonanni D, Sini M, Goyal P, Marini E, Pors K,Adinolfi S, Zonari D, Festuccia C, Wahlgren WY, Friemann R, Bagnati R, Boschi D,Oliaro-Bosso S, Lolli ML. Potent and selective aldo-keto reductase 1C3 (AKR1C3)inhibitors based on the benzoisoxazole moiety: application of a bioisostericscaffold hopping approach to flufenamic acid. Eur J Med Chem. 2018 Apr25;150:930-945. 
 
7: North RA, Horne CR, Davies JS, Remus DM, Muscroft-Taylor AC, Goyal P,Wahlgren WY, Ramaswamy S, Friemann R, Dobson RCJ. "Just a spoonful of sugar...":import of sialic acid across bacterial cell membranes. Biophys Rev. 2018Apr;10(2):219-227. 
 
8: Caing-Carlsson R, Goyal P, Sharma A, Ghosh S, Setty TG, North RA, Friemann R,Ramaswamy S. Crystal structure of N-acetylmannosamine kinase from Fusobacteriumnucleatum. Acta Crystallogr F Struct Biol Commun. 2017 Jun 1;73(Pt 6):356-362. 
 
9: Sainas S, Pippione AC, Giorgis M, Lupino E, Goyal P, Ramondetti C, BuccinnàB, Piccinini M, Braga RC, Andrade CH, Andersson M, Moritzer AC, Friemann R,Mensa S, Al-Kadaraghi S, Boschi D, Lolli ML. Design, synthesis, biologicalevaluation and X-ray structural studies of potent human dihydroorotatedehydrogenase inhibitors based on hydroxylated azole scaffolds. Eur J Med Chem.2017 Mar 31;129:287-302. 
 
10: Van den Broeck I, Goyal P, Remaut H. Insights in peptide diffusion channelsfrom the bacterial amyloid secretor CsgG. Channels (Austin). 2015;9(2):65-7. 
 
11: Goyal P, Krasteva PV, Van Gerven N, Gubellini F, Van den Broeck I,Troupiotis-Tsaïlaki A, Jonckheere W, Péhau-Arnaudet G, Pinkner JS, Chapman MR,Hultgren SJ, Howorka S, Fronzes R, Remaut H. Structural and mechanistic insightsinto the bacterial amyloid secretion channel CsgG. Nature. 2014 Dec11;516(7530):250-3. 
 
12: Maindola P, Raina R, Goyal P, Atmakuri K, Ojha A, Gupta S, Christie PJ, IyerLM, Aravind L, Arockiasamy A. Multiple enzymatic activities of ParB/Srxsuperfamily mediate sexual conflict among conjugative plasmids. Nat Commun. 2014Oct 31;5:5322. 
 
13: Van Gerven N, Goyal P, Vandenbussche G, De Kerpel M, Jonckheere W, De GreveH, Remaut H. Secretion and functional display of fusion proteins through thecurli biogenesis pathway. Mol Microbiol. 2014 Mar;91(5):1022-35. 
 
14: Goyal P, Van Gerven N, Jonckheere W, Remaut H. Crystallization andpreliminary X-ray crystallographic analysis of the curli transporter CsgG. ActaCrystallogr Sect F Struct Biol Cryst Commun. 2013 Dec;69(Pt 12):1349-53. 
 
15: Ielasi FS, Goyal P, Sleutel M, Wohlkonig A, Willaert RG. The mannose-specific lectin domains of Flo1p from Saccharomyces cerevisiae and Lg-Flo1p fromS. pastorianus: crystallization and preliminary X-ray diffraction analysis ofthe adhesin-carbohydrate complexes. Acta Crystallogr Sect F Struct Biol CrystCommun. 2013 Jul;69(Pt 7):779-82.