INTERNATIONAL PATENTS:

1.          Process for the simultaneous production of artemisinin and essential oil from the plant Artemisia annua.

D. C. Jain, S. Tandon, R. S. Bhakuni, M. S. Siddique, A. P. Kahol, R. P. Sharma, S. Kumar and A. K. Bhattacharya.

EPC Patent No. 97402349.1-2101 dt. 06.10.1997; Granted EP 908460 A1 19990414.

US Patent No. 5,955,084, Sep. 21, 1999.

Canadian Patent No. 2, 218, 44; Oct 16, 1997.

2.          Method for the use of α-arteether as an antibacterial and antifungal agent.

S. Kumar, S. P. S. Khanuja, T. R. S. Kumar, D. C. Jain, S. Srivastava, A. K. Bhattacharya, D. Saikia, A. K. Shasany, M. P. Darokar and R. P. Sharma.

US Patent No. 6,127,405, Oct. 3, 2000; Granted US 6127405 A 20001003.

3.     New methanone-(3',4',5'-trimethoxy) phenyl, 1-naphthyl, 2-O-4''-ethyl but-2''-enoate useful as synthetic plant growth regulators.

S. P. S. Khanuja , M. P. Darokar, A. Garg, T. Padmapriya, A. K. Shasany, A. S. Negi, S. K . Chattopadhyay, S. Srivastava and A. K. Bhattacharya.

WO2005063677-A1; US2005181950-A1; AU2003290421-A1; IN200400504-P1; US7135590-B2; CN1946671-A; JP2007535467-W; JP4382041-B2; CA2552205-C; IN250039-B; ZA200605368-A; CN100519507-C; AU2003290421-B2.

4.     Process for regioselective demethylation of p-methoxy group in phenolic ester and diaryl ketone moieties.

A. S. Negi, S. K. Chattopadhyay, S. Srivastava and A. K. Bhattacharya.

US Patent No. 7,053,218, May 30, 2006; Granted US 2006052463 A1 20060309.

5.     Preparation of gallic acid derivative as a plant growth regulator.

S. P. S. Khanuja, M. P. Darokar, A. Garg, T. Padmapriya, A. K. Shasany, A. S. Negi, S. K. Chattopadhyay, S. Srivastava and A. K. Bhattacharya.

PCT Int. Appl. (2005), WO 2005063677 A1 20050714.

6.     Dihydroartemisinin-peptidyl-vinylaminophosphonates hybrid molecules and process for preparation thereof.

A. K. Bhattacharya, A. Mohmmed, P. Malhotra, K. C. Rana, H. R. Chand, M.  Kalamuddin and I. K. Polanki.

2013-INV-0078 (US/PTC Patent Filed).

7.     Process for synthesis of piperidine alkaloids from D-glucal and D-galactal.

A. K. Bhattacharya and H. R. Chand.

PCT Int. Appl. (2015), WO 2015170339 A1 20151112.

8.     Process for isolation of diterpene from Polyalthia longifolia.

A. K. Bhattacharya, H. R. Chand and M. V. Deshpande.

2014-INV-006 (US/PTC Patent Filed).

9.     Antimalarial compounds and process for preparation thereof.

        A. K. Bhattacharya, E. K. Aratikatla, K. Srivastava and A. Manhas.

        PCT Int. Appl. (2016), WO 2016063301 A2 20160428.

10.   A method for the synthesis of norepinephrine alkaloids and its analogs as         antimalarial agents.

        A. K. Bhattacharya, E. K. Aratikatla, K. Srivastava and A. Manhas.

US Application No. 15/520989; EP Application No. 15805326.4; PCT/IN2015/050140.

11.   Novel process for the synthesis of an antimalarial drug.

A. K. Bhattacharya and H. R. Chand.

2014-INV-0101 (US/PTC Patent Filed).

12.   Process for the isolation of bioactive sesquiterpenes from the plant Vernonia arborea.

A. K. Bhattacharya and I. K. Polanki.

        2015-INV-0023 (US/PTC Patent Filed).

13.   In-vitro & in-vivo inhibition of postprandial hyperglycemia & breast cancer by use of Mentha arvensis L. leaves extract.

S. B. Agawane, V. S. Gupta, M. J. Kulkarni and A. K. Bhattacharya.

2015-NCL-0037 (US/PTC Patent Filed).

14.   Angiopterlactone B, analogues and process for synthesis thereof.

A. K. Bhattacharya and T. K. Kotammagari.

        PCT Int. Appl. (2017), WO 2017077549 A1 20170511.

15.   Preparation of glycolactams compounds, process for preparing them and uses thereof as intermediates for piperidine alkaloids.

A. K. Bhattacharya and H. R. Chand.

PCT Int. Appl. (2017), WO 2017191657 A1 20171109.

16.   A method for the synthesis of C-arylation product of benzopyranones and 1,4-pyranones, a key precursor for the synthesis of cytotoxic compounds.

A. K. Bhattacharya and S. Paul.

US/PCT Patent Filed.

17.   Artemisinic acid glycoconjugate compounds, process for preparation and use thereof.

        A. K. Bhattacharya, T. K. Kotammagari and M. K. Santra.

PCT Int. Appl. (2019), WO 2019135257 A1 20190711.

18. Novel antimalarial artemisinin-dipeptidyl vinyl based compounds, process for preparation and their use for drug resistant malaria.

        A. K. Bhattacharya, E. K. Aratikatla, P. Malhotra and A. Mohmmed.

        PCT Int. Appl. (2019), WO 2019202609 A1 20191024.

19.   Novel antimalarial compounds and process for preparation thereof.

A. K. Bhattacharya and S. Paul.

US/PCT Patent Filed (2022).

INDIAN PATENTS:

1.     An improved process for the preparation of artemisinin.

A. K. Bhattacharya, M. S. Siddique, R. S. Bhakuni, D. C. Jain and R. P. Sharma.

        Indian Patent No. 2458/DEL/95 dt. 29.12.1995; Granted IN 184682 A120000923.

2.     An improved process for the preparation of sodium p-(12b-dihydroartemisinoxy) methyl benzoate [Sodium b-artelinate], a water-soluble potent antimalarial compound.

M. Shrimali, A. K. Bhattacharya, D. C. Jain, R. S. Bhakuni and R. P. Sharma.

Indian Patent No. 2618/DEL/96 dt. 29.11.1996; Granted IN 185198 A1 20001202.

3.     A method for the use of a-arteether as an efficient fourth generation antibacterial and antifungal drug.

S. Kumar, S. P. S. Khanuja, T. R. Santha Kumar, D. C. Jain, S. Srivastava, A. K. Bhattacharya, D. Saikia, A. K. Shasany, M. P. Darokar and R. P. Sharma.

Indian Patent No. 1967/DEL/98.

4.     Process for the preparation of artethers from dihydroartemisinin.

A. K. Bhattacharya, S. P. S. Khanuja and D. C. Jain.

Indian Patent No. NF-550/20; Granted IN 2003DE00542 A 20070713.

5.     Gallic acid derivative and process of preparing the same.

S. P. S. Khanuja, M. P. Darokar, A. Garg, T. Padma, A. K. Shashnay, A. S. Negi, S. K. Chattopadhyay, S. Srivastava and A. K. Bhattacharya.

        Indian Patent No. NF 508/2003.

6.     A process for regioselective demethylation of p-methoxy group in phenolic ester and diaryl ketone moieties.

A. S. Negi, S. K. Chattopadhyay, S. Srivastava and A. K. Bhattacharya.

Indian Patent No. 199 NF 2004; Granted IN 2004DE01699 A 20060818; 244222 24.11.2010.

7.     Dihydroartemisinin-peptidyl-vinylaminophosphonates hybrid molecules and process for preparation thereof.

A. K. Bhattacharya, A. Mohmmed, P. Malhotra, K. C. Rana, H. R. Chand, M.  Kalamuddin and I. K. Polanki.

Indian Patent No. 2245/DEL/2013, 29.07.2013.

8.     Novel process for synthesis of piperidine alkaloids.

A. K. Bhattacharya and H. R. Chand.

Indian Patent No. 1250/DEL/2014, 09.05.2014; Granted Indian Pat. Appl. (2016), IN 2014DE01250 A 20160831.

9.     Process for isolation of diterpene from Polyalthia longifolia.

A. K. Bhattacharya, H. R. Chand and M. V. Deshpande.

Indian Patent No. 2114/DEL/2014, 25.07.2014; Granted Indian Pat. Appl. (2016), IN 2014DE02114 A 20160129.

10.   Stereoselective synthesis of artemisinin ether derivatives.

A. K. Bhattacharya and H. R. Chand.

Indian Patent No. 3079/DEL/2014, 29.10.2014; Granted Indian Pat. Appl. (2016), IN 2014DE03079 A 20160831.

11.   Novel anti-malarial agents.

        A. K. Bhattacharya, E. K. Aratikatla, K. Srivastava and A. Manhas.

        Indian Patent Filed 3005/DEL/2014, 21.10.2014; Granted Indian Pat. Appl. (2016),           IN 2014DE03005 A 20160831.

12.   Process for the isolation of bioactive sesquiterpenes from the plant Vernonia arborea.

A. K. Bhattacharya and I. K. Polanki.

        Indian Patent Filed 1024/DEL/2015, 13.04.2015.

13.   In-vitro & in-vivo inhibition of postprandial hyperglycemia & breast cancer by use of Mentha arvensis L. leaves extract. 

S. B. Agawane, V. S. Gupta, M. J. Kulkarni and A. K. Bhattacharya.

Indian Patent Filed 2015-NCL-0037.

14.   Angiopterlactone B, analogues and process for synthesis thereof.

A. K. Bhattacharya and T. K. Kotammagari.

        Indian Patent Filed 3557/DEL/2015, 02.11.2015.

15.   Novel glycolactams derivative and process for preparation thereof.

A. K. Bhattacharya and H. R. Chand.

        Indian Patent Application No. (2018) 201611015813 A 20180209 dt. 06.05.2016.

16.   A method for the synthesis of C-arylation product of benzopyranones and 1,4-pyranones.

A. K. Bhattacharya and S. Paul.

Indian Patent Application No. 201611027580 dt. 12.08.2016; Indian Pat. Appl. (2018), IN 201611027580 A 20180316.

17.   Artemisinic acid glycoconjugate compounds, process for preparation and use thereof.

A. K. Bhattacharya, T. K. Kotammagari and M. K. Santra.

        Indian Patent Application No 201811000290.

18. Novel antimalarial artemisinin-dipeptidyl vinyl based compounds, process for preparation and their use for drug resistant malaria.

        A. K. Bhattacharya, E. K. Aratikatla, P. Malhotra and A. Mohmmed.

        Indian Patent Application No. 201811014401, Indian Pat. Appl. (2019), IN     201811014401 A 20191018.

19.   Novel antimalarial compounds and process for preparation thereof.

         A. K. Bhattacharya and S. Paul.

        Indian Patent Filed. NF-2022.