Manoj K Singh , Rijith Jayarajan , Swati Varshney , Sindhuri Upadrasta , Archana Singh , Rajni Yadav , Vinod Scaria , Shantanu Sengupta , Dhanasekaran Shanmugam , Shalimar , Sridhar Sivasubbu , Sheetal Gandotra And Chetana Sachidanandan , Chronic systemic exposure to IL6 leads to deregulation of glycolysis and fat accumulation in the zebrafish liver, Biochim Biophys Acta Mol Cell Biol Lipids ., , (2021), DOI:10.1016/j.bbalip.2021.158905.
Salwa Naushin, Viren Sardana, Rajat Ujjainiya, Nitin Bhatheja, Rintu Kutum, Akash Kumar Bhaskar, Shalini Pradhan, Satyartha Prakash, Raju Khan, Birendra Singh Rawat, Karthik Bharadwaj Tallapaka, Mahesh Anumalla, Giriraj Ratan Chandak, Amit Lahiri, Susanta Kar, Shrikant Ramesh Mulay, Madhav Nilakanth Mugale, Mrigank Srivastava, Shaziya Khan, Anjali Srivastava, Bhawana Tomar, Murugan Veerapandian, Ganesh Venkatachalam, Selvamani Raja Vijayakumar, Ajay Agarwal, Dinesh Gupta, Prakash M Halami, Muthukumar Serva Peddha, Gopinath M Sundaram, Ravindra P Veeranna, Anirban Pal, Vinay Kumar Agarwal, Anil Ku Maurya, Ranvijay Kumar Singh, Ashok Kumar Raman, Suresh Kumar Anandasadagopan, Parimala Karuppanan, Subramanian Venkatesan, Harish Kumar Sardana, Anamika Kothari, Rishabh Jain, Anupama Thakur, Devendra Singh Parihar, Anas Saifi, Jasleen Kaur, Virendra Kumar, Avinash Mishra, Iranna Gogeri, Geethavani Rayasam, Praveen Singh, Rahul Chakraborty, Gaura Chaturvedi, Pinreddy Karunakar, Rohit Yadav, Sunanda Singhmar, Dayanidhi Singh, Sharmistha Sarkar, Purbasha Bhattacharya, Sundaram Acharya, Vandana Singh, Shweta Verma, Drishti Soni, Surabhi Seth, Sakshi Vashisht, Sarita Thakran, Firdaus Fatima, Akash Pratap Singh, Akanksha Sharma, Babita Sharma, Manikandan Subramanian, Yogendra S Padwad, Vipin Hallan, Vikram Patial, Damanpreet Singh, Narendra Vijay Tripude, Partha Chakrabarti, Sujay Krishna Maity, Dipyaman Ganguly, Jit Sarkar, Sistla Ramakrishna, Balthu Narender Kumar, Kiran A Kumar, Sumit G Gandhi, Piyush Singh Jamwal, Rekha Chouhan, Vijay Lakshmi Jamwal, Nitika Kapoor, Debashish Ghosh, Ghanshyam Thakkar, Umakanta Subudhi, Pradip Sen, Saumya Ray Chaudhury, Rashmi Kumar, Pawan Gupta, Amit Tuli, Deepak Sharma, Rajesh P Ringe, Amarnarayan D, Mahesh Kulkarni, Dhansekaran Shanmugam, Mahesh S Dharne, Sayed G Dastager, Rakesh Joshi, Amita P Patil, Sachin N Mahajan, Abujunaid Habib Khan, Vasudev Wagh, Rakesh Kumar Yadav, Ajinkya Khilari, Mayuri Bhadange, Arvindkumar H Chaurasiya, Shabda E Kulsange, Krishna Khairnar, Shilpa Paranjape, Jatin Kalita, Narahari G Sastry, Tridip Phukan, Prasenjit Manna, Wahengbam Romi, Pankaj Bharali, Dibyajyoti Ozah, Ravi Kumar Sahu, Elapavalooru VSSK Babu, Rajeev Sukumaran, Aiswarya R Nair, Prajeesh Kooloth Valappil, Anoop Puthiyamadam, Adarsh Velayudhanpillai, Kalpana Chodankar, Samir Damare, Yennapu Madhavi, Ved Varun Aggarwal, Sumit Dahiya, Anurag Agrawal, Debasis Dash Is a corresponding author And Shantanu Sengupta , Insights from a Pan India Sero-Epidemiological survey (Phenome-India Cohort) for SARS-CoV2, eLife., , (2021), DOI:Apr 20, 2021.
Amit Kumar Sahu, abc Madhukar S. Said, ad Tejashri Hingamire, ac Megha Gaur, f Abujunaid Khan, abc Dhanasekaran Shanmugam, ac Vitthal T. Barvkar, e Mahesh S. Dharne And abc Atul A. Bhardef and Syed G. Dastager , Approach to nigericin derivatives and their therapeutic potentia, RSC Advances., , (2020), DOI:10.1039/d0ra05137c.
Alok Tanala Patra, Tejashri Hingamire, Meenakshi A. Belekar, Aoli Xiong, Gowtham Subramanian, Zbynek Bozdech, Peter Preiser, Dhanasekaran Shanmugam And Rajesh Chandramohanadas, Whole-Cell Phenotypic Screening of Medicines for Malaria Venture Pathogen Box Identifies Specific Inhibitors of Plasmodium falciparum Late-Stage Development and Egress, American Society of Microbiology., , (2020), DOI:10.1128/AAC.01802-19.
Lionel Urán Landaburu, Ariel J Berenstein, Santiago Videla, Parag Maru, Dhanasekaran Shanmugam, Ariel Chernomoretz And Fernán Agüero, TDR Targets 6: driving drug discovery for human pathogens through intensive chemogenomic data integration, Nucleic Acids Research ( NAR )., , (2019), DOI:10.1093/nar/gkz999.
Aishwarya A. Betgiri, Sameer N. Jadhav, Mrunalini Pawde, Anurag Shukla, Chandrashekhar Mote, Prashant D. Pawar, Dhanasekaran Shanmugam And Krishnendu Kundu, Mitochondrial cytochrome oxidase C subunit III (cox3) gene as a sensitive and specific target for molecular detection of Babesia gibsoni infection in dogs, Experimental Parasitology., Volume 206, (2019), DOI:https://doi.org/10.1016/j.exppara.2019.107771.
Shivapurkar R, Hingamire T, Kulkarni AS, Rajamohanan PR, Reddy DS And Shanmugam D, Evaluating antimalarial efficacy by tracking glycolysis in Plasmodium
falciparum using NMR spectroscopy, Scientific Reports., , (2018), DOI:10.1038/s41598-018-36197-3.
Subramanian G, Belekar MA, Shukla A, Tong JX, Sinha A, Chu TTT, Kulkarni AS, Preiser PR, Reddy DS, Tan KSW, Shanmugam D And Chandramohanadas R, Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules, mSphere., 3, (2018), DOI:10.1128/mSphere.00534-17.
Paresh R. Athawale, Gorakhnath R. Jachak, Anurag Shukla, Dhanasekaran Shanmugam And and D. Srinivasa Reddy, Efforts To Access the Potent Antitrypanosomal Marine Natural Product Janadolide: Synthesis of Des-tert-butyl Janadolide and Its Biological Evaluation, ACS Omega., 3, 2383 - 2389 (2018).
Anurag Shukla, Kellen L. Olszewski, Manuel Llinás, Leah M. Rommereim, Barbara A. Fox, David J. Bzik, Dong Xia, Jonathan Wastling, Daniel Beiting, David S. Roos And Dhanasekaran Shanmugam, Glycolysis is important for optimal asexual growth and formation of mature tissue cysts by Toxoplasma gondii, International Journal for Parasitology., , (2018).
https://doi.org/10.1016/j.ijpara.2018.05.013
Bendre AD, Suresh CG, Shanmugam D And Ramasamy S., Structural insights into the unique inhibitory mechanism of Kunitz type trypsin inhibitor from Cicer arietinum L, J Biomol Struct Dyn., , 1 - 38 (2018), DOI:10.1080/07391102.2018.1494633.
Rahul Salunke, Tobias Mourier, Manidipa Banerjee, Arnab Pain And Dhanasekaran Shanmugam, Highly diverged novel subunit composition of apicomplexan F-type ATP synthase identified from Toxoplasma gondii, PlOS Biology., 16, e2006128 (2018), DOI:https://doi.org/10.1371/journal.pbio.2006128.
Pronay Das, Palak Babbar, Nipun Malhotra, Manmohan Sharma, Goraknath R. Jachak, Rajesh G. Gonnade , Dhanasekaran Shanmugam, Karl Harlos, Manickam Yogavel, Amit Sharma And D. Srinivasa Reddy, Specific Stereoisomeric Conformations Determine the Drug Potency of Cladosporin Scaffold against Malarial Parasite, J. Med. Chem., 61, 5664 - 5678 (2018), DOI:10.1021/acs.jmedchem.8b00565.
Ashish A. Chinchansure, Manisha Arkile, Anurag Shukla, Dhanasekaran Shanmugam, Dhiman Sarkar And Swati P. Joshi, Leucas mollissima, a Source of Bioactive Compounds with Antimalarial and Antimycobacterium Activities, Planta Med Lett., , (2015), DOI:10.1055/s-0035-1557830.
Yong H WooCorresponding Author, Hifzur Ansari, Thomas D Otto, Christen M Klinger, Martin Kolisko, Jan Michálek, Alka Saxena, Dhanasekaran Shanmugam, Annageldi Tayyrov, Alaguraj Veluchamy, Shahjahan Ali, Axel Bernal, Javier del Campo, Jaromír Cihlá?, Pavel Flegontov, Sebastian G Gornik, Eva Hajdušková, Aleš Horák, Jan Janouškovec, Nicholas J Katris, Fred D Mast, Diego Miranda-Saavedra, Tobias Mourier, Raeece Naeem, Mridul Nair, Aswini K Panigrahi, Neil D Rawlings, Eriko Padron-Regalado, Abhinay Ramaprasad, Nadira Samad, Aleš Tom?ala, Jon Wilkes, Daniel E Neafsey, Christian Doerig, Chris Bowler, Patrick J Keeling, David S Roos, Joel B Dacks, Thomas J Templeton, Ross F Waller, Julius Lukeš, Miroslav Oborník And Arnab PainCorresponding Author, Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites, eLife., , (2015), DOI:http://dx.doi.org/10.7554/eLife.06974.
I. Q. H. Phan, D. R. Davies, N. S. Moretti, D. Shanmugam, I. Cestari, A. Anupama, J. W. Fairman, T. E. Edwards, K. Stuart And S. Schenkman and P. J. Myler, Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures, MOLECULAR PARASITOLOGY., , (2015), DOI:10.1107/S2053230X15004185.
Kedar B. Batkulwar, Sneha B. Bansode, Gouri V. Patil, Rashmi K. Godbole, Rubina S. Kazi, Subashchandrabose Chinnathambi, Dhanasekaran Shanmugam And Mahesh J. Kulkarni, Investigation of phosphoproteome in RAGE signaling, PROTEOMICS., , (2014), DOI:10.1002/pmic.201400169.
Reid J. A, Vermont J. S, Cotton A. J, Harris D, Hill-Cawthorne A. G And Ko, Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy, PLOS Pathogens., 8(3):e1002567, (2012).
Magarinos MP, Carmona SJ, Crowther GJ, Ralph SA, Roos DS, Shanmugam D And Van Voorhis WC, Aguero F. TDR Targets: a chemogenomics resource for neglected diseases, Nuc. Acid Res. 40:D1118-27. ., , (2012).
Shanmugam D, Ralph SA, Carmona SJ, Crowther GJ, Roos DS And Ferna, Integrating and mining helminth genomes to discover and prioritize novel therapeutic targets. (2012). In Press ? ? titled Chemo- and Immuno-therapeutic advances for treatment and control of helminthic infections. , Wiley Book Series (Vol 4) on ?Drug Discovery in Infectious Diseases., , (2012).
Coyne S. R, Hannick L, Shanmugam D, Hostetler B. J, Brami D, Joardar S. V, Johnson J, Radune D, Singh I, Kumar U, Saier M, Wang Y, Cai H, Gu J, Mather W. M, Vaidya B. A, Wilkes E. D, Rajagopalan V, Asai J. D, Pearson G. C, Findly C. R, Dickerson W. H, Badger J, Wu M, Martens C, Van de Peer Y, Roos S. D, Cassidy- Hanley M. D And Clark G. T. , Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free- living relatives and a host species: insights into adoption of a parasitic lifestyle and prospects for disease control. , Genome Biology. 12:R100. ., , (2011).
Fern, ez Robledo JA, Caler E, Matsuzaki M, Keeling PJ, Shanmugam D, Roos DS And Vasta GR. , The search for the missing link: A relic plastid in Perkinsus, Int. J. Parasitol., 41(12), 1217 - 29 (2011).
Fischer S, Brunk P. B, Chen F, Gao X, Iodice B. J, Shanmugam D, Roos S. D And Stoeckert J. C., Using OrthoMCL to assign proteins to OrthoMCL-DB groups or to cluster proteomes into new ortholog groups, Current Protocols in Bioinformatics. Chapter 6; Unit 6.12., , (2011).
Jaffe EK, Shanmugam D, Gardberg A, Dieterich S, Sankaran B, Stewart L, Myler P And Roos DS., Crystal structure of Toxoplasma gondii Porphobilinogen synthase: Insights on octameric structure and porphobilinogen formation, J. Biol. Chem., 286(17), 15298 - 307 (2011).
Bahl A, Davis PH, Behnke M, Dzierszinski F, Jagalur M, Chen F, Shanmugam D, White MW, Kulp D And Roos DS., A novel multi-functional oligonucleotide microarray for Toxoplasma gondii , BMC Genomics., 0.877083333333, (2010).
Crowther GJ, Shanmugam D, Carmona SJ, Doyle MA, Hertz-Fowler C, Berriman M, Nwaka S, Ralph SA, Roos DS And Van Voorhis WC , Aguero F. Identification of attractive drug targets in neglected-disease pathogens using an in silico approach. , PLOS Neglected Tropical Diseases. ., 4(8):e804. Doi:10.1371 /journal.pntd.0000804. , (2010).
Shanmugam D, Wu B, Ursula Ramirez, Jaffe E And Roos DS. , Plastid associated porphobilinogen synthase from Toxoplasma gondii: Kinetic and structural properties validate therapeutic potential, J. Biol. Chem., 285(29), 22122 - 31 (2010).
Aguero F, Al-Lazikani B, Aslett M, Berriman M, Buckner FS, Campbell RK, Carmona S, Carruthers IM, Chan AWE, Chen F, Crowther GJ, Hertz-Fowler C, Hopkins AL, McAllister G, Nwaka S, Overington JP, Pain A, Paolini GV, Pieper U, Ralph SA, Riechers A, Roos DS, Sali A, Shanmugam D, Suzuki T, Van Voorhis WC And Verlinde CL., Genomic-scale Prioritization of Drug Targets: the TDR Targets database, Nat. Rev. Drug Discov. ., 7, 900 - 907 (2008).
Vathsala P.G., Pramanik, A., Dhanasekaran, S., Usha Devi C., Pillai C.R., Subbarao S.K., Ghosh S.K., Tewari S.N., Sathyanarayanan T.S., Deshp, e P.R., Mishra G.C., Ranjit M.R., Dash A.P., Rangarajan P.N. And Padmanaban, G. Widespread occurrence of the Plasmodium falciparum chloroquine-resistant transporter (PFCRT) gene haplotype SVMNT in P. falciparum malaria in India. , Am. J. Trop. Med. Hyg. ., 70(3), 256 - 259 (2004).
Dhanasekaran, S., Ch, ra, N.R Sagar, B.K.C., Rangarajan P.N. And Padmanaban, G. , J. Biol. Chem., 279(8), 6934 - 6942 (2004).
Varadharajan S., Dhanasekaran S., Bonday Z.Q., Rangarajan P.N. And Padmanaban, G. Involvement of , Biochem. J., 367(Pt 2), 321 - 327 (2002).
BondayZ.Q.*, Dhanasekaran S.*, Rangarajan P.N. And Padmanaban, , G. Import of host , Nature Med., 6(8), 898 - 903 (2000).
