Research Group Publications
 
  • Patil HS, Jadhav DD, Paul A, Mulani FA, Karegaonkar SJ And Thulasiram HV, Regioselective and Efficient Enzymatic Synthesis of Antimicrobial Andrographolide Derivatives, Bioorg. Med. Chem. Lett., 28, 1132 - 1137 (2018).
  • Aarthy, T , Mulani, FA , Pandreka, A , Kumar, A , Nandikol, SS , Haldar, S , Thulasiram And HV, Tracing the biosynthetic origin of limonoids and their functional groups through stable isotope labeling and inhibition in neem tree (Azadirachta indica) cell suspension, BMC Plant Biology., 18, 230 (2018).
  • Patil HS, Jadhav DD, Paul A, Mulani FA, Karegaonkar SJ And Thulasiram HV, Lipase catalyzed synthesis of antimicrobial andrographolide derivatives, Data in brief., 18, 1134 - 1141 (2018).
  • Kumar D, Haldar S, Gorain M, Kumar S, Mulani FA, Yadav AS, Miele L, Thulasiram HV And Kundu GC, Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway, BMC Cancer., 18, 52 (2018).
  • Swamy, VP; Thulasiram, HV, Rastrelli, F , ; Saielli And G , Ion pairing in 1-butyl-3-methylpyridinium halide ionic liquids studied using NMR and DFT calculations, Phys. Chem. Chem. Phys., 20, 11470 - 11480 (2018).
  • Sandholu, AS , Mohole, M , Duax, WL , Thulasiram, HV , Sengupta, D , Kulkarni And K, Dynamics of loops at the substrate entry channel determine the specificity of iridoid synthases, FEBS Letters., 592, 2624 - 2635 (2018).
  • B Natarajan B, HS Kalsi HS, P Godbole P, N Malankar N, A Thiagarayaselvam A, Siddappa S, Thulasiram HV, Chakrabarti SK And Banerjee AK, MiRNA160 is Associated with Local Defense and Systemic Acquired Resistance of Potato Against Phytophthora Infestans Infection, J. Exp. Bot., 69, 2023 - 2036 (2018).
  • Limbkar K, Dhenge A, Jadhav DD, Thulasiram HV, Kale V And Limaye L, Data on the effect of oral feeding of Arachidonic acid or Docosahexanoic acid on haematopoiesis in mice, Data in brief., 14, 551 - 557 (2017).
  • Soujanya KN, Siva R, Kumara PM, Srimany A, Ravikanth G, Mulani FA, Aarthy T, Thulasiram HV, Santhoshkumar TR, Karaba N Nataraja And Uma Shaanker R, Camptothecin-producing endophytic bacteria from Pyrenacantha volubilis Hook.(Icacinaceae): A possible role of a plasmid in the production of camptothecin, Phytomedicine., 36, 160 - 167 (2017).
  • Benke SN, Thulasiram HV And Gopi HN, Potent Antimicrobial Activity of Lipidated Short ?, ??Hybrid Peptides, ChemMedChem., 12, 1610 - 1615 (2017).
  • Limbkar K, Dhenge A, Jadhav DD, Thulasiram HV, Kale V And Limaye L, Oral feeding with polyunsaturated fatty acids fosters hematopoiesis and thrombopoiesis in healthy and bone marrow-transplanted mice. The Journal of nutritional biochemistry, The Journal of nutritional biochemistry., 47, 94 - 105 (2017).
  • Gade M, Chaudhary PM, Thulasiram HV And Kikkeri R, Engineering Cell Surface Glycans with Carbohydrate Enantiomers to Alter Bacterial Binding and Adhesion, ChemistrySelect., 2, 8865 - 8869 (2017).
  • Durge A, Jadaun P, Wadhwani A, Chinchansure AA, Said M, Thulasiram HV, Swati P Joshi And Smita S Kulkarni, Acetone and methanol fruit extracts of Terminalia paniculata inhibit HIV-1 infection in vitro, Natural product research., 31, 1468 - 1471 (2017).
  • Deshmukh AB, Bai S, Aarthy T, Kazi RS, Banarjee R, Rathore R, Vijayakumar MV, Thulasiram HV, Manoj Kumar Bhat And MJ Kulkarni, Methylglyoxal attenuates insulin signaling and downregulates the enzymes involved in cholesterol biosynthesis, Molecular BioSystems., 13, 2338 - 2349 (2017).
  • Toraskar S, Gade M, Sangabathuni S, Thulasiram HV And Kikkeri R. , Exploring the Influence of Shapes and Heterogeneity of Glyco?Gold Nanoparticles on Bacterial Binding for Preventing Infections, ChemMedChem., 12, 1116 - 1124 (2017).
  • Jadhav DD, Patil HS, Chaya PS And Thulasiram HV. , Fungal Mediated Kinetic Resolution of Racemic Acetates to (R)- Alcohols using Fusarium proliferatum, Tetrahedron Lett., 57, 4563 - 4567 (2016), DOI:10.1016/j.tetlet.2016.08.084.
  • Anand A, Ramesha HJ, Beedkar S, Singh P, Joshi R, Mulani FA, Dholakia BB, Punekar SA, Gade WN, Thulasiram HV And Giri AP., Comparative functional characterization of eugenol synthase from four different Ocimum species: Implications on eugenol accumulation, Biochimica et Biophysica Acta -Proteins and Proteomics., 1864, 1539 - 1547 (2016).
  • Kumar D, Kumar S, Gorain M, Tomar D, Patil HS, Radharani NNV, Kumar TVS, Patil, TV, Thulasiram HV And Kundu GC., Notch1-MAPK Signaling Axis Regulates CD133+ Cancer Stem Cell-Mediated Melanoma Growth and Angiogenesis, J. Invest. Dermatol., xx, xxxx - xxxx (2016), DOI:10.1016/j.jid.2016.07.024.
  • Kushwaha P, Khedgikar V, Haldar S, Gautam J, Mulani FA, ? Thulasiram HV And Trivedi R. , Azadirachta indica triterpenoids promote osteoblast differentiation and mineralization in vitro and in vivo, Bioorg. Med. Chem. Lett., 26, 3719 - 3724 (2016), DOI:10.1016/j.bmcl.2016.05.076.
  • Ramesha HJ, Anand A, Beedkar S, Dholakia BB, Punekar SA, Kalunke RM, Gade WN, Thulasiram HV And Giri AP., Functional characterization and transient expression manipulation of a new sesquiterpene synthase involved in ?-caryophyllene accumulation in Ocimum, Biochem. Biophys. Res. Commun., 473, 265 - 271 (2016).
  • Shinde SS, Navale GR, Said MS And Thulasiram HV. , Stereoselective quenching of cedryl carbocation in epicedrol biosynthesis, Tetrahedron Lett., 57, 1161 - 1164 (2016).
  • Singh P, Ramesha HJ, Agawane SB, Vannuruswamy G, Korwar AM, Anand A, Dhayude VS, Shaikh ML, Joshi RS, Boppanna R, Kulkarni MJ, Thulasiram HV And Giri AP. , Dual Role of Eugenol in Inhibiting Advanced Glycation End Products in Diabetes: Proteomic and Mechanistic Insights, Sci. Rep. (Nature group publication)., 6, 18798 (2016), DOI:10.1038/srep18798.
  • Pandreka A, Dandekar DS, Haldar S, Uttara V, Vijayashree SG, Mulani FA, Aarthy T And Thulasiram HV. , Triterpenoid Profiling and Functional Characterization of the Initial Genes Involved in Isoprenoid Biosynthesis in Neem (Azadirachta indica), BMC Plant Biology., 15:214, 1 - 14 (2015), DOI:10.1186/s12870-015-0593-3.
  • Srivastava PL, Daramwar PP, Krithika R, Pandreka A, Shankar SS And Thulasiram HV, Functional Characterization of Novel Sesquiterpene Synthases from Indian Sandalwood, Santalum album, Scientific Reports (Nature Group)., 5, 10095 (2015), DOI:10.1038/srep10095.
  • Haldar S, Mulani FA, Aarthy T And Thulasiram HV, 11?-Hydroxylation on the Basic Limonoid Skeleton by Fungal Biocatalyst, Cunninghamella echinulata, J. Org. Chem., 80, 6490 - 6495 (2015), DOI:10.1021/acs.joc.5b00417.
  • Ponnusamy S, Haldar S, Mulani FA, Zinjarde S, Thulasiram HV And Ravikumar A, Gedunin and Azadiradione: Human Pancreatic alpha-Amylase Inhibiting Limonoids from Neem (Azadirachta indica) as anti-diabetic agents, PLOS ONE., 10 (10), e0140113 (2015), DOI:10.1371/journal.pone.0140113.
  • Nair A, Kolet SP, Thulasiram HV And Bhargava S, Role of methyl jasmonate in the expression of mycorrhizal induced resistance against Fusariumoxysporum in tomato plants, Physiological and Molecular Plant Pathology., (Accepted), (2015), DOI:10.1016/j.pmpp.2015.10.002.
  • Deshmukh A, Gore B, Thulasiram HV And Swamy VP, Recyclable ionic liquid iodinating reagent for solvent free, regioselective iodination of activated aromatic and heteroaromatic amines, RSC Advances., Accepted, (2015), DOI:10.1039/C5RA14702F.
  • Krithika R, Srivastava PL, Rani B, Kolet SP, Chopade M, Mantri S And Thulasiram HV, Characterization of 10-Hydroxygeraniol Dehydrogenase from Catharanthus roseus Reveals Cascaded Enzymatic Activity in Iridoid Biosynthesis, Scientific Reports (Nature Group)., 5, 8258 (2015), DOI:10.1038/srep08258.
  • Chaudhary PM, Sangabhatuni S, Murthy RV, Paul A, Thulasiram HV And Kikkeri R, Assessing the Effect of Different Shapes of Glyco-gold nanoparticles on Bacterial Adhesion and Infections, Chem. Commun., Accepted, (2015), DOI:10.1039/C5CC05238F.
  • Patel N, Patel P, Shuchishweta V. Kendurkar SV And Thulasiram HV and Khan BM, Overexpression of squalene synthase in Withania somnifera leads to enhanced withanolide biosynthesis, Plant Cell Tiss. Organ Cult., Published online: 13 May 2015, (2015), DOI:10.1007/s11240-015-0778-3.
  • Gade M, Paul A, Alex C, Choudhury D, Thulasiram HV And Kikkeri R , Supramolecular Scaffolds on Glass Slides as Sugar Based Rewritable Sensor for Bacteria, Chem. Commun., 51, 6346 - 6349 (2015).
  • Kolekar YM, Vannuruswamy G, Sneha B Bansode SB, Santhakumari B And Thulasiram HV and Kulkarni MJ , Investigation of Antiglycation Activity of Isoprenaline, RSC Adv., 5, 25051 - 25058 (2015).
  • Nair A, Kolet SP, Thulasiram HV And Bhargava S, Systemic jasmonic acid modulation in mycorrhizal tomato plants and its role in induced resistance against Alternaria alternata, Plant Biology., Published online: 2 JAN 2015, (2015), DOI:10.1111/plb.12277.
  • Kolet SP, Jadhav DD, Priyadarshini B, Swarge BN And Thulasiram HV., Fungi mediated production and practical purification of (R)-(-)-3-quinuclidinol, Tetrahedron Lett., 55, 5911 - 5914 (2014).
  • Haldar S, Kale B, Jadhav DD And Thulasiram HV., Lipase mediated separation of triterpene structural isomers, ?- and ?-amyrin, Tetrahedron Lett., 55, 3122 - 3125 (2014).
  • Haldar S, Mulani FA, Aarthy T, Dandekar DS And Thulasiram HV. , Expedient preparative isolation and tandem mass spectrometric characterization of C-seco triterpenoids from Neem oil, J. Chromatogr. A., 1366, 1 - 14 (2014).
  • Joshi RS, Wagh TP, Sharma N, Mulani FA, Sonavane U, Thulasiram HV, Joshi R, Gupta VS And Giri AP, Way toward “Dietary Pesticides”: Molecular Investigation of Insecticidal Action of Caffeic Acid against Helicoverpa armigera, J. Agric. Food Chem., 62, 10847 - 10854 (2014), DOI:10.1021/jf503437r.
  • Haldar S, Kolet SP, Dandekar DS, Kale BS, Gonnade R And Thulasiram HV, Biocatalyst mediated functionalization of salannin, an insecticidal limonoid, RSC Advances., 4, 27661 - 27664 (2014).
  • Kolet SP, Haldar S, Niloferjahan S And Thulasiram HV. , Mucor hiemalis mediated 14?-hydroxylation on steroids: In vivo and in vitro investigations of 14?-hydroxylase activity, Steroids., 85, 6 - 12 (2014).
  • Singh P, Ramesha HJ, Sarate P, Thulasiram HV, Kulkarni MJ And Giri AP. , Interaction between Ocimum kilimandscharicum and Helicoverpa armigera unveils promising insecticidal metabolites, PLOS ONE., 9, e104377 (2014).
  • Bhogale S, Mahajan A, Natarajan B, ? Rajabhoj M, Thulasiram HV And Banerjee AK., A graft-transmissible microRNA that modulates plant architecture and tuberization in potato (Solanum tuberosum ssp andigena), Plant Physiol., 164, 1011 - 1027 (2014).
  • Daramwar PP, Srivastava PL, Kolet SP And Thulasiram HV. , Biocatalyst mediated regio- and stereo-selective hydroxylation and epoxidation of (Z)-?-Santalol, Org. Biomol. Chem., 12, 1048 - 1051 (2014).
  • Jadhav S, Paphale PB, Thulasiram HV And Bhargava S., Polyketide synthesis in tobacco plants transformed with Plumbago zeylanica hexaketide synthase, Phytochemistry., 98, 92 - 100 (2014).
  • Kesavan SK, Bhat S, Golegaonkar SB, Jagadeeshaprasad MG, Deshmukh AB, Patil HS, Bhosale SD, Shaikh ML, Thulasiram HV, Boppana R And Kulkarni MJ., Proteome wide reduction in AGE modification in STZ induced diabetic mice by hydralazine mediated transglycation, Sci. Report., 3, 2941, 1 - 10 (2013).
  • Shankar S, Benke SN, Nagendra N, Srivastava PL, Thulasiram HV And Gopi HN., Self-Assembly to Function: Design, Synthesis and Broad Spectrum Antimicrobial Properties of Short Hybrid E-Vinylogous Lipopeptides, J. Med. Chem., 56, 8468 - 8474 (2013).
  • Haldar S, Kolet SP And Thulasiram HV., Biocatalysis: Fungi mediated Selective 12 beta- or 17 beta- Hydroxylation on the Basic Limonoid Skeleton, Green Chem., 15, 1311 - 1317 (2013).
  • Haldar S, Phapale PB, Kolet SP And Thulasiram HV., Expedient preparative isolation, quantification and characterization of limonoids from Neem fruits, Anal. Methods., 5, 5386 - 5391 (2013).
  • Kolet SP, Niloferjahan S, HaldarS, Gonnade R And Thulasiram HV. , Biocatalyst Mediated Production of 6 beta,11 alpha-dihydroxy derivatives of 4-ene-3-one Steroids, Steroids., 78, 1152 - 1158 (2013).
  • Haldar S, Kumar S, Kolet SP, Patil HS, Kumar D, Kundu G And Thulasiram HV., One-Pot Fluorescent Labeling Protocol for Complex Hydroxylated Bioactive Natural Products, J. Org. Chem., 78, 10192 - 10202 (2013).
  • Kumar S, Patil HS, Sharma P, Kumar D, Dasari S, Puranik VG, Thulasiram HV And Kundu GC., Andrographolide inhibits osteopontin expression and breast tumor growth through down regulation of PI3 kinase/Akt signaling pathway, Curr. Mol. Med., 12, 952 - 966 (2012).
  • Alam A, Haldar S, Thulasiram HV, Kumar R, Goyal M, Iqbal MS, Pal C, Dey S, Bindu S, Sarkar S, Pal U, Maiti NC And Bandyopadhyay U., Novel anti-inflammatory activity of epoxyazadiradione against macrophage migration inhibitory factor: inhibition of tautomerase and proinflammatory activities of macrophage migration inhibitory factor, J. Biol. Chem., 287, 24844 - 24861 (2012).
  • Daramwar PP, Srivastava PL, Priyadarshini B And Thulasiram HV., Preparative separation of alpha- and beta-santalenes and (Z)-alpha- and (Z)-beta-santalols using silver nitrate-impregnated silica gel medium pressure liquid chromatography and analysis of sandalwood oil, Analyst., 137, 4564 - 70 (2012).
  • Daramwar PP, Rincy R, Niloferjahan S, Krithika R, Gulati A, Yadav A, Sharma R And Thulasiram HV., Transformation of (±)-lavandulol and (±)-tetrahydrolavandulol by a fungal strain Rhizopus oryzae, Bioresource Technol., 115, 70 - 74 (2012).
  • SathishYadav KN, Adsul MG, Bastawde KB, Jadhav DD, Thulasiram HV And Gokhale DV., Induction, purification and characterization of cold active lipase from Yarrowia lipolytica NCIM 3639, Bioresource Technol., 102, 10663 - 10670 (2011).
  • Suresh KK, Bhosale SD, Thulasiram HV And Kulkarni MJ., Comparative and chemical proteomic approaches reveal gatifloxacin deregulates enzymes involved in glucose metabolism, J. Toxicol. Sci., 36, 787 - 796 (2011).
  • Ajit Singh, Nar Singh Chauhan, H. V. Thulasiram And VibhaTaneja and Rakesh Sharma., Identification of two flavin monooxygenases from an effluent treatment plant sludge metagenomic library, Bioresource Technol., 101, 8481 - 8484 (2010).
  • Thulasiram HV, Erickson HK And Poulter CD., A Common Mechanism for Branching, Cyclopropanation, and Cyclobutanation Reactions in the Isoprenoid Biosynthetic Pathway, J. Am. Chem. Soc., 130, 1966 - 1971 (2008).
  • Thulasiram HV, Erickson HK And Poulter CD., Chimeras of Two Isoprenoid Synthases Catalyze All Four Coupling Reactions in Isoprenoid Biosynthesis, Science., 316, 73 - 76 (2007).
  • Thulasiram HV And Poulter CD., Farnesyl Diphosphate Synthase: The Art of Compromise between Stereoselectivity and Substrate Selectivity, J. Am. Chem. Soc., 128, 15819 - 15823 (2006).
  • Thulasiram HV, Phan RM, Rivera SB And Poulter CD., Synthesis of deuterium-labeled derivatives of dimethylallyl diphosphate, J. Org. Chem., 71, 1739 - 1741 (2006).
  • Plapp BV, Thulasiram HV, Berst KB And Kaduce TL., Recombinant Mouse Alcohol Dehydrogenase 1: Kinetic Mechanism, Substrate Specificity and Oxidation of 20-Hydroxy-eicosatetraenoic acid, Enzymology and Molecular Biology of Carbonyl Metabolism., 13, 123 - 133 (2006).
  • Thulasiram HV And Madyastha KM., Transformation of a monoterpene ketone, piperitenone, and related terpenoids using Mucor piriformis, Can. J. Microbiol., 51, 447 - 454 (2005).
  • Venkataramaiah TH And Plapp BV., Formamides mimic aldehydes and inhibit liver alcohol dehydrogenases and ethanol metabolism, J. Biol. Chem., 278, 36699 - 706 (2003).
  • Thulasiram HV, Bhat VB And Madyastha MK., Effect of ring size in R-(+)-pulegone-mediated hepatotoxicity: studies on the metabolism of R-(+)-4-methyl-2-(1-methylethylidene)-cyclopentanone and DL-camphorone in rats, Drug Metab. Dispos., 29, 821 - 9 (2001).
  • Thulasiram HV, Gadad AK And Madyastha MK. , Role of C-5 chiral center in R-(+)-pulegone-mediated hepatotoxicity: metabolic disposition and toxicity of 5, 5-dimethyl-2-(1-Methylethylidene)-cyclohexanone in rats, Drug Metab. Dispos., 28, 833 - 44 (2000).
  • Madyastha KM And Thulasiram HV., Transformation of a monoterpene ketone, (R)-(+)-pulegone, a potent hepatotoxin, in Mucor piriformis, J. Agric. Food Chem., 47, 1203 - 7 (1999).