Research Group Publications
 
  • Shinde DR, Krishna GR And and Marelli UK, Metal-Free One-Pot Domino Synthesis of Oxazolidinethione Derivatives of Quaternary Amino Acids from ?-Amino Esters and Aldehydes Using CS2, J. Org. Chem., , (2024), DOI:https://doi.org/10.1021/acs.joc.3c02217.
  • Dangi A, Pande B, Agrawal S, Sarkar D, Vamkudoth KR And Marelli UK, Total synthesis, structure elucidation and expanded bioactivity of icosalide A: effect of lipophilicity and ester to amide substitution on its bioactivity, Org. Biomol. Chem., 21, 5725 - 5731 (2023), DOI:DOI https://doi.org/10.1039/D3OB00809F.
  • Dangi A And Marelli UK, Exploration of N?arylation of backbone amides as a novel tool for conformational modification in peptides, Chem. Eur. J., 29, (2023), DOI:https://doi.org/10.1002/chem.202301803.
  • Kanungo SS, Mishra AK, Mhamane NB, Marelli UK, Kumar D And Gopinath CS, Possible Fine-Tuning of Methane Activation toward C2 Oxygenates by 3d-Transition Metal-Ions Doped Nano-Ceria-Zirconia, Inorg Chem., 61, 19577 - 19587 (2022), DOI:https://doi.org/10.1021/acs.inorgchem.2c03493.
  • Alam MN, Dash SR, Mukherjee A, Pandole S, Marelli UK, Vanka K And Maity P, [1,3]-Claisen Rearrangement via Removable Functional Group Mediated Radical Stabilization, Org Lett., 23, 890 - 895 (2021), DOI:https://doi.org/10.1021/acs.orglett.0c04109.
  • Dangi A, Balmik AA, Ghorpade AK, Gorantla NV, Sonawane SK, Chinnathambi S And Marelli UK, Residue-based propensity of aggregation in the Tau amyloidogenic hexapeptides AcPHF6* and AcPHF6, RSC Adv., 10, 27331 - 27335 (2020), DOI:DOI https://doi.org/10.1039/D0RA03809A.
  • Balmik AA, Chidambaram H, Dangi A, Marelli UK And Chinnathambi S, HDAC6 ZnF UBP as the Modifier of Tau Structure and Function, Biochemistry., 59, 4546 - 4562 (2020), DOI:https://doi.org/10.1021/acs.biochem.0c00585.
  • Balmik AA, Das R, Dangi A, Gorantla NV, Marelli UK And Chinnathambi S, Melatonin interacts with repeat domain of Tau to mediate disaggregation of paired helical filaments, Biochim Biophys Acta Gen Subj., 1864, 129467 (2020), DOI:https://doi.org/10.1016/j.bbagen.2019.129467.
  • Sonawane SK, Chidambaram H, Boral D, Gorantla NV, Balmik AA, Dangi A, Ramasamy S, Marelli UK And Chinnathambi S., EGCG impedes human Tau aggregation and interacts with Tau, EGCG impedes human Tau aggregation and interacts with Tau., 10, 12579 (2020), DOI:https://doi.org/10.1038/s41598-020-69429-6.
  • Dan VM, J S V, C J S, Sanawar R, Lekshmi A, Kumar RA, Santhosh Kumar TR, Marelli UK, Dastager SG And Pillai MR, Molecular Networking and Whole-Genome Analysis Aid Discovery of an Angucycline That Inactivates mTORC1/C2 and Induces Programmed Cell Death, ACS Chem Biol., 15, 780 - 788 (2020), DOI:https://doi.org/10.1021/acschembio.0c00026.
  • Meena CL, Singh D, Weinmüller M, Reichart F, Dangi A, Marelli UK, Zahler S And Sanjayan GJ, Novel cilengitide-based cyclic RGD peptides as ?v?3 integrin inhibitors, Bioorg Med Chem Lett., 30, 127039 (2020), DOI:https://doi.org/10.1016/j.bmcl.2020.127039.
  • Das TK, Madica K, Krishnan J, Marelli UK And Biju AT, Heterocyclic Carbene Catalysis Exploiting Oxidative Imine Umpolung for the Generation of Imidoyl Azoliums, J Org Chem., 85, 5114 - 5121 (2020), DOI:https://doi.org/10.1021/acs.joc.0c00360.
  • Das TK, Ghosh A, Balanna K, Behera P, Gonnade RG, Marelli UK, Das AK And Biju AT, N-Heterocyclic Carbene-Catalyzed Umpolung of Imines for the Enantioselective Synthesis of Dihydroquinoxalines, ACS Catal., 9, 4065 - 4071 (2019), DOI:https://doi.org/10.1021/acscatal.9b00737.
  • Reichart F, Maltsev OV, Kapp TG, Räder AFB, Weinmüller M, Marelli UK, Notni J, Wurzer A, Beck R, Wester HJ, Steiger K, Di Maro S, Di Leva FS, Marinelli L, Nieberler M, Reuning U, Schwaiger M And Kessler H., Selective Targeting of Integrin ?v?8 by a Highly Active Cyclic Peptide, J. Med. Chem., 62, 2024 - 2037 (2019), DOI:https://doi.org/10.1021/acs.jmedchem.8b01588.
  • Dandela R, Tothadi S, Marelli UK And Nangia A, Systematic synthesis of a 6-component organic-salt alloy of naftopidil, and pentanary, quaternary and ternary multicomponent crystals, IUCrJ., 5, 816 - 822 (2018), DOI:https://doi.org/10.1107/S2052252518014057.
  • Mukherjee S, Ghosh A, Marelli UK And Biju AT, N-Heterocyclic Carbene-Catalyzed Michael–Michael–Lactonization Cascade for the Enantioselective Synthesis of Tricyclic ?-Lactones, Org. Lett., 18, 2952 - 2955 (2018), DOI:https://doi.org/10.1021/acs.orglett.8b00998.
  • Di Leva FS, Tomassi S, Di Maro S, Reichart F, Notni J, Dangi A, Marelli UK, Brancaccio D, Merlino F, Wester HJ, Novellino E, Kessler H And Marinelli L., From a Helix to a Small Cycle: Metadynamics-Inspired ?v?6 Integrin Selective Ligands, Angew. Chem. Int. Ed., 57, 1 - 6 (2018), DOI:https://doi.org/10.1002/anie.201803250.
  • Tobias G. Kapp, Francesco Saverio Di Leva, Johannes Notni, Andreas F. B. Räder, Maximilian Fottner, Florian Reichart, Dominik Reich, Alexander Wurzer, Katja Steiger, Ettore Novellino, Udaya Kiran Marelli, Hans-Jürgen Wester, Luciana Marinelli And and Horst Kessler, N-methylation of isoDGR Peptides: Discovery of a Selective a5b1-Integrin Ligand as a Potent Tumor Imaging Agent, J. Med. Chem., 61, 2490 - 2499 (2018), DOI:DOI: 10.1021/acs.jmedchem.7b01752.
  • Michael Weinmüller, Rechenmacher, Udaya Kiran Marelli, Florian Reichart, Tobias G. Kapp, Andreas B. Räder, Francesco Saverio Di Leva, Luciana Marinelli, Ettore Novellino, José M. Muñoz Félix, Kairbaan Hodivala-Dilke, Adi Schumacher, Joseph Fanous, Chaim Gilon, Amnon Hoffman And Horst Kessler, Overcoming the lack of oral availability of cyclic hexapeptides: Design of a new selective and orally available ligand for the integrin avb3, Angew. Chem. Int. Ed., 56, 16405 - 16409 (2017), DOI:DOI:10.1002/anie.201709709.
  • Minying Cai, Udaya Kiran Marelli, Blake Mertz , Johannes G. Beck, Florian Opperer, Florian Rechenmacher, Horst Kessler And Victor J. Hruby, Structural Insights into Selective Ligand–Receptor Interactions Leading to Receptor Inactivation Utilizing Selective Melanocortin 3 Receptor Antagonists, Biochemistry., 56, 4201 - 4209 (2017), DOI:10.1021/acs.biochem.7b00407.
  • K. Kashinath, Gorakhnath R. Jachak, Paresh R. Athawale, Udaya Kiran Marelli, Rajesh G. Gonnade And D. Srinivasa Reddy, Total Synthesis of the Marine Natural Product Solomonamide B Necessitates Stereochemical Revision, Org. Lett., , (2016), DOI:10.1021/acs.orglett.6b01395.
  • Oleg V. Maltsev, Udaya Kiran Marelli, Tobias G. Kapp, Francesco Saverio Di?Leva, Salvatore Di?Maro, Markus Nieberler, Ute Reuning, Markus Schwaiger, Ettore Novellino, Luciana Marinelli And Horst Kessler, Stable Peptides Instead of Stapled Peptides: Highly Potent avb6-Selective Integrin Ligands, Angew. Chem. Int. Ed., 55, 1535 - 1539 (2016), DOI:10.1002/anie.201508709.
  • Lekshmi R. Nath, Jaggaiah N. Gorantla, Arun Kumar T. Thulasidasan, Vinod Vijayakurup, Shabna Shah, Shabna Anwer, Sophia M. Joseph, Jayesh Antony, Kollery Suresh Veena, Sankar Sundaram, Udaya K. Marelli, Ravi S. Lankalapalli And Ruby John Anto, Evaluation of uttroside B, a saponin from Solanum nigrum Linn, as a promising chemotherapeutic agent against hepatocellular carcinoma, Scientific Reports., 6:36318, 1 - 13 (2016), DOI:10.1038/srep36318.
  • Minying Cai, Udaya Kiran Marelli, Jennifer Bao, Johannes G Beck, Florian Opperer, Florian Rechenmacher, Kaitlyn R McLeod, Morgan R Zingsheim, Lucas Doedens, Horst Kessler And Victor J Hruby, Systematic Backbone Conformational Constraints on a Cyclic Melanotropin Ligand Leads to Highly Selective Ligands for Multiple Melanocortin Receptors, J. Med. Chem., 58, 6359 - 6367 (2015), DOI:10.1021/acs.jmedchem.5b00102.
  • Udaya Kiran Marelli, Oded Ovadia, Andreas Oliver Frank, Jayanta Chatterjee, Chaim Gilon, Amnon Hoffman And Horst Kessler, Cis-peptide bonds: A key for intestinal permeability of peptides?, Chem. Eur. J., 21, 15148 - 15152 (2015), DOI:10.1002/chem.201501600.
  • Udaya Kiran Marelli, Jacqueline Bezençon, Eduard Puig, Beat Ernst And Horst Kessler, Enantiomeric Cyclic Peptides with Different Caco-2 Permeability Suggest Carrier-Mediated Transport, Chem. Eur. J., 21, 8023 - 8027 (2015), DOI:10.1002/chem.201501270.
  • Udaya Kiran Marelli, Andreas O Frank, Bernhard Wahl, Valeria La Pietra, Ettore Novellino, Luciana Marinelli, Eberhardt Herdtweck, Michael Groll And Horst Kessler, Receptor-Bound Conformation of Cilengitide Better Represented by Its Solution-State Structure than the Solid-State Structure, Chem. Eur. J., 20, 14201 - 14206 (2014), DOI:10.1002/chem.201403839.
  • Alexander Bochen, Udaya Kiran Marelli, Elke Otto, Diego Pallarola, Carlos Mas-Moruno, Francesco Saverio Di Leva, Heike Boehm, Joachim P Spatz, Ettore Novellino, Horst Kessler And Luciana Marinelli, Biselectivity of isoDGR peptides for fibronectin binding integrin subtypes a5b1 and avb6: conformational control through flanking amino acids, J. Med. Chem., 4, 1509 - 1519 (2013), DOI:10.1021/jm301221x.
  • Udaya Kiran Marelli, Florian Rechenmacher, Tariq Rashad Ali Sobahi, Carlos Mas-Moruno And Horst Kessler, Tumor targeting via integrin ligands, Front Oncol., 3, (2013), DOI:10.3389/fonc.2013.00222.
  • Sai Chaitanya Chiliveri, Sonu Kumar, Udaya Kiran Marelli And Mandar V Deshmukh, Backbone and sidechain methyl Ile (d1), Leu and Val chemical shift assignments of RDE-4 (1–243), an RNA interference initiation protein in C. elegans, Biomol. NMR Assign., 6, 143 - 146 (2012), DOI:10.1007/s12104-011-9343-0.
  • Johannes G Beck, Jayanta Chatterjee, Burkhardt Laufer, Marelli Udaya Kiran, Andreas O Frank, Stefanie Neubauer, Oded Ovadia, Sarit Greenberg, Chaim Gilon, Amnon Hoffman And Horst Kessler, Intestinal permeability of cyclic peptides: common key backbone motifs identified, J. Am. Chem. Soc., 134, 12125 - 12133 (2012), DOI:10.1021/ja303200d.
  • Srivari Chandrasekhar, Nayani Kiranmai, Marelli Udaya Kiran, Ambure Sharada Devi, Gangireddy Pavan Kumar Reddy, Mohammed Idris And Bharatam Jagadeesh, Novel helical foldamers: organized heterogeneous backbone folding in 1: 1 a/nucleoside-derived-b-amino acid sequences, Chem. Commun., 46, 6962 - 6964 (2010), DOI:10.1039/C0CC01724H.
  • Tushar K Chakraborty, K Srinivasa Rao, M Udaya Kiran And B Jagadeesh, Stabilization of b-hairpin structures via inter-strand pi-pi and hydrogen bond interactions in a-, b-, g-hybrid peptides, Tet. Lett., 50, 4350 - 4353 (2009), DOI:10.1016/j.tetlet.2009.05.024.
  • Grit Kummerlöwe, Marelli Udaya Kiran And Burkhard Luy, Covalently Cross-linked Gelatin Allows Chiral Distinction at Elevated Temperatures and in DMSO, Chem. Eur. J., 15, 12192 - 12195 (2009), DOI:10.1002/chem.200902193.
  • Bharatam Jagadeesh, Marelli Udaya Kiran, Ambadi Sudhakar And Srivari Chandrasekhar, Backbone Regulation Mimicry by b-Peptidic Foldamers: Formation of a 10-Helix in a Mixed 6-Strand/14-Helix Conformational Pool, Chem. Eur. J., 15, 12592 - 12595 (2009), DOI:10.1002/chem.200902332.
  • Marelli Udaya Kiran, Ambadi Sudhakar, Jochen Klages, Grit Kummerlo?we, Burkhard Luy And Bharatam Jagadeesh, RDC enhanced NMR spectroscopy in organic solvent media: the importance for the experimental determination of periodic hydrogen bonded secondary structures, J. Am. Chem. Soc., 131, 15590 - 15591 (2009), DOI:10.1021/ja906796v.
  • Tushar K Chakraborty, K Srinivasa Rao, M Udaya Kiran And B Jagadeesh, Nucleation of the b-hairpin structure in a linear hybrid peptide containing a-, b-and g-amino acids, Tet. Lett., 49, 2228 - 2231 (2008), DOI:10.1016/j.tetlet.2008.02.048.
  • Srivari Chandrasekhar, Birudaraju Saritha, Police Naresh, Marelli Udayakiran, Chada Raji Reddy And Bharatam Jagadeesh, Synthesis and Conformational Studies of a Hybrid Cyclic Peptide Based on cis-b-Furanoid Sugar Amino Acid (FSAA) and Ornithine, Helv. Chem. Acta., 91, 1267 - 1276 (2008), DOI:10.1002/hlca.200890138.
  • Srivari Chandrasekhar, Chennamaneni Lohitha Rao, Marepally Srinivasa Reddy, Ganti Dattatreya Sharma, Marelli Udaya Kiran, Police Naresh, Gunturu Krishna Chaitanya, Kotamarthi Bhanuprakash And Bharatam Jagadeesh, b-Sugar Aminoxy Peptides As Rigid Secondary Structural Scaffolds, J. Org. Chem., 73, 9443 - 9446 (2008), DOI:10.1021/jo801810z.
  • Srivari Chandrasekhar, Ambadi Sudhakar, Marelli Udaya Kiran, Bathini Nagendra Babu And Bharatam Jagadeesh, b-Strand mimetics: formation of bend-strands in oligomers of enantiomeric b-amino acids, Tet. Lett., 49, 7368 - 7371 (2008), DOI:10.1016/j.tetlet.2008.10.031.
  • S Chandrasekhar, G Pavan Kumar Reddy, M Udaya Kiran, Ch Nagesh And B Jagadeesh, Nucleoside derived amino acids (NDA) in foldamer chemistry: synthesis and conformational studies of homooligomers of modified AZT, Tet. Lett., 49, 2969 - 2973 (2008), DOI:10.1016/j.tetlet.2008.03.001.
  • TK Chakraborty, S Uday Kumar, B Krishna Mohan, G Dattatreya Sarma, M Udaya Kiran And B Jagadeesh, Synthesis and conformational studies of 3, 4-di-O-acylated furanoid sugar amino acid-containing analogs of the receptor binding inhibitor of vasoactive intestinal peptide, Tet. Lett., 48, 6945 - 6950 (2007), DOI:10.1016/j.tetlet.2007.07.158.
  • Palakodety Radha Krishna, PV Narasimha Reddy, A Sreeshailam, M Uday Kiran And B Jagdeesh, The Baylis–Hillman reaction: a strategic tool for the synthesis of higher-carbon sugars, Tet. Lett., 48, 6466 - 6470 (2007), DOI:10.1016/j.tetlet.2007.07.067.
  • Srivari Chandrasekhar, Bathini Nagendra Babu, Anabathula Prabhakar, Ambadi Sudhakar, Marepally Srinivasa Reddy, Marelli Udaya Kiran And Bharatam Jagadeesh, Oligomers of cis-b-norbornene amino acid: Formation of b-strand mimetics, Chem. Commun., , 1548 - 1550 (2006), DOI:10.1039/B518420G.
  • Gullapalli Kumaraswamy, Mogilisetti Padmaja, Bekkam Markondaiah, Nivedita Jena, Balasubramanian Sridhar And Marelli Udaya Kiran, Oppolzer sultam directed aldol as a key step for the stereoselective syntheses of antitumor antibiotic belactosin C and its synthetic congeners, J. Org. Chem., 71, 337 - 340 (2006), DOI:10.1021/jo0516887.