Total synthesis and methodology development Lab

 CSIR- National Chemical Laboratory, Pune

 Welcome to SBM group     

Dr. Santosh B. Mhaske

Principal Scientist and Associate Professor(AcSIR)
Division of Organic Chemistry
CSIR-National Chemical Laboratory (NCL)
Dr. Homi Bhabha Road
Pune 411008, India
Phone: +91 20 2590 2440
Lab: +91 20 2590 2573
Fax: +91 20 2590 2629
E-mail: sb.mhaske@ncl.res.in  

 

 

 
 

 

Recent Publications:

 

Figure 1
Go to Organic Letters
"Nickel-Catalyzed Direct Synthesis of N-Substituted Indoles from Amino Alcohols and Alcohols"

Vinita Yadav, Sayali G. Jagtap, Ekambaram Balaraman*, Santosh B. Mhaske*

Org. Lett. (2022)

 

 

Go to journal home page - Tetrahedron Letters

"Construction of tetrahydrobenzo[f]quinoline scaffolds via polar [4 + 2]-Cycloaddition reaction with arynes as dienophiles"

Virat G.Pandya, Santosh B.Mhaske

Tetrahedron Letters (2022)

 

 

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"Phosphine-Free Manganese(II)-Catalyst Enables Acceptorless Dehydrogenative Coupling of Alcohols with Indole"

Vinita Yadav, Ekambaram Balaraman, Santosh B. Mhaske

Adv. Synth. Catal., (2021)

 

 

Go to The Journal of Organic Chemistry
Abstract Image

"Annulation of Enals with Carbamoylpropiolates via NHC-Catalyzed Enolate Pathway: Access to Functionalized Maleimides/Iso-maleimides and Synthesis of Aspergillus FH-X-213"

Amol B. Viveki,§ Mahesh D. Pol,§ Priyanka Halder, Sameer R. Sonavane, and Santosh B. Mhaske* (§Equal Contribution)

J. Org. Chem., 86, 14, 9466–9477 (2021) 

 

 

 

"Photoactivable Prodrug for Simultaneous Release of Mertansine, and CO along with a BODIPY Derivative as a Luminescent Marker in Mitochondria: A Proof of Concept for NIR Image-Guided Cancer Therapy"

Rajeshwari Tiwari‡, Prashant S. Shinde‡,Sreejesh Sreedharan‡, Anik Kumar Dey, Katherine A. Vallis*, Santosh B. Mhaske*, Sumit Kumar Pramanik* and Amitava Das* (‡Equal Contribution)

Chem. Sci., 12, 2667-2673 (2021)

 

Graphical abstract: Construction of unique SCF3-containing building blocks via allylic alkylation of Morita–Baylis–Hillman adducts

"Construction of Unique SCF3-Containing Building Blocks via Allylic Alkylation of Morita-Baylis-Hillman Adducts"   

 Priyanka Halder, Mahesh D. Pol, Milind M. Ahire and Santosh B. Mhaske*

Org. Biomol. Chem., 18, 2085 - 2093 (2020)

 

 

 

 

Graphical abstract: para-Selective copper-catalyzed C(sp2)–H amidation/dimerization of anilides via a radical pathway

"para-Selective copper-catalyzed C(sp2)–H amidation/dimerization of anilides via a radical pathway" 

 Amol B. Viveki, Dnyaneshwar N. Garad, Rajesh G. Gonnade and Santosh B. Mhaske* 

 Chem. Commun., 56, 1565 - 1568 (2020)

 

Graphical abstract: Stereoselective construction of deoxy-cruciferane alkaloids by NHC-catalyzed intramolecular annulation of homoenolate with quinazolinone
"Stereoselective construction of deoxy-cruciferane alkaloids by NHC-catalyzed intramolecular annulation of homoenolate with quinazolinone"  

 Milind M. Ahire, Mahesh D. Pol, Dattatry S. Kavale, Rajesh G. Gonnade and Santosh B. Mhaske*

  Org. Biomol. Chem., 17, 7135 - 7139 (2019)

 

Go to Volume 84, Issue 4

“Ru-Catalyzed Regioselective Cascade Annulation of Acrylamides with 2-Alkynoates for the Synthesis of Various 6-Oxo Nicotinic Acid Esters”

 Dnyaneshwar N. Garad and Santosh B. Mhaske*

 J. Org. Chem., 84, 1863 - 1870 (2019)