Research

Total synthesis and methodology development

  • Total Synthesis
  • Catalysis and new methods
  • Biomolecular Chemistry
  • Chemical Biology
  • Natural Products
  • Process Chemistry

 

Research Interest:

  • Total synthesis and SAR studies of antimalarial natural products, their simplified analogues and natural product hybrids.
  • Synthesis of combinatorial libraries of selected analogues of simplified natural products in search of potential antimalarial drug candidates.
  • Development of valuable synthetic methodologies using organo-cataysis, organo-metalic chemistry, arynes and N-heterocyclic Carbenes
  • Development of novel and efficient Organocatalysts.
  • Renewable Bioresources to value added chemicals/materials


  • We are engaged in research on Natural Products Chemistry, Drug Discovery and Development of related Synthetic Methodologies. Our special interest is in the synthesis of natural products and drugs active against neglected tropical diseases and development of novel and competent synthetic methodologies using organo-cataysis, organo-metalic chemistry, arynes and N-heterocyclic Carbenes. Transformation of renewable bioresources to value added chemicals/materials will be also an important part of our studies.

 

  • Organic chemistry research is a powerful tool to address problems of social importance. Accordingly all our programs will be directed towards the studies on the total synthesis of natural products active against neglected tropical diseases and on an effective conversion of biomass to useful chemicals/materials. Presently we are working on the total synthesis of antimalarial natural products and further generating a library of their simplified and rationalized analogs for SAR studies based on computational analysis. Our prime aim is to develop natural product based potential drug candidates active against malaria. These studies will certainly develop new chemistry and useful synthetic methodologies as well as better understanding of the disease. Organocatalysis and an efficient transformation of renewable bioresources to value added chemicals/materials will also be an important part of our studies.